“…Human [152] a-1-antitrypsin Over-expression leads to decrease oocyte quality Human [153,154] Vascular endothelial growth factor (VEGF) Over-expression leads to decrease oocyte quality and fertilization rate Human [155] Leptin Over-expression leads to decrease oocyte quality and fertilization rate Human [156][157][158] Endothelin-2 Increase oocyte maturation and fertilization rate Human [159,160] Homocystein Over-expression leads to decrease oocyte quality Human [161,162] Lactoferrin Increase oocyte quality, fertilization and cleavage rate Human [163] D-aspartic acid Increase fertilization rate Human [164] Prorenin Decrease fertilization rate Human [165] Heparan sulfate proteoglycan perlecan (HSPG) Oocyte quality, increase fertilization rate and growth factor binding and apoptosis regulation Human [59, 166,167] Fibronectin-binding protein A Cell adhesion and fertilization Human Amphiregulin, heparan sulfate proteoglycan 2; tumor necrosis factor a induced protein 6 (TNFAIP6); plasminogen, lymphatic vessel endothelial hyaluronan receptor 1, a-1-microglobulin/ bikuninprecursor (AMBP), SERPINA1, apolipoprotein A1 (APOA1) and haptoglobin (HP)…”