Correlation between antimullerian hormone level before and after laparoscopic ovarian autologous PRP injections

Abstract

Aim: Randomized clinical trial aimed to know the possible correlation between laparoscopic ovarian autologous PRP injection and AMH level. Patients and Methods: Fifty-one Sudanese subfertile women attended to Banoon Fertility Center, Khartoum, Sudan, during the period from January 2018-June 2019 selected randomly and exposed to laparoscopic ovarian autologous PRP injection. AMH level of every participant measured before and after 3 months of administration of PRP to the ovaries. Results and Conclusion:We measured size of correlation between AMH level pre and post exposure of ovaries to PRP, AMH level increased in 33.3% (17) of the participants after PRP injection. Size of correlation = 0.64 which represent moderate positive correlation. The p-value was < .00001. The result is significant at p < .05. Further studies must be carried on with large sample size and involving different ethnic group. We are very grateful to all participated women whom voluntarily accept to engage in the study and to all cooperative staff at banoon fertility center.

Effect of autologous platelet rich plasma on anti-mullerian hormone and antral follicle count in sub fertile women with poor ovarian reserve

“…Melo et al conducted a prospective controlled, nonrandomized comparative study in Venezuela on 46 women with low ovarian reserve prior to assisted reproductive technology (ART). 12 The mean BMI was 24.6±1.2 kg/m 2 , within normal limit as like present study. They investigated the impact of a 3-month course of intra cortical injections of autologous PRP upon ovarian reserve markers versus no intervention in women with low ovarian reserve.…”

“…The findings of this study are in accordance with Melo et al who found significant (p<0.001) improvement of post-PRP, AMH level at three month of ovarian PRP in 63.00% of participants. 12 AFC on ultrasound following PRP treatment increased in 75.00%. FSH level dropped in 33.00% of the women receiving PRP.…”

“…11 Salih et al conducted a randomized clinical trial to show significant increase in AMH level in Sudanese subfertile women following laparoscopic ovarian autologous PRP injection. 12 Melo et al investigated, in a non-randomized comparative study in Venezuela, the impact of three cycles monthly intra-cortical ovarian PRP injections on ovarian reserve markers. 13 Women treated with PRP experienced a significant improvement in follicle stimulating hormone (FSH), AMH and antral follicle count (AFC).…”