A cross-sectional study was carried out at the H. Adam Malik hospital in Medan. Purposive sampling was used to identify 55 research patients receiving hemodialysis (HD). Structured questionnaire interviews with patients were used to collect epidemiology data. Medical records and retested laboratory results were used to collect data on hemoglobin, qualitative C Reactive Protein (CRP), Blood urea nitrogen (BUN), and creatinine. The majority (72.7 %) of participants were male, with the 60–69 year age group accounting for 30.90%; Karo is the most ethnic group (41.8%), and hypertension is the most prevalent ailment (43.60%). The mean duration of HD was 36.00 months, with a hemoglobin (Hb) level of 9.37 g/dl. It can be shown that there is a negative and weak correlation between Hb and HD duration (r = -0.27) that is significant (p = 0.49) and has a coefficient of determination of 7%.