Correlation between fat accumulation and fecal microbiota in crossbred pigs

Li, Xin; Li, Mengyu; Han, Jinyi; Liu, Chuang; Han, Xuelei; Wang, Kejun; Qiao, Ruimin; Li, Xiuling; Li, Xinjian

doi:10.1007/s12275-022-2218-5

Cited by 3 publications

(1 citation statement)

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“…Other published studies have shown that manipulating the gut microbiome can improve feed efficiency and average daily gain [ 74 , 75 , 76 , 77 ], as well as improve herd health [ 78 , 79 , 80 , 81 , 82 ]. Insights on the impact of the gut microbiome on more specific traits, such as adiposity [ 83 , 84 , 85 ] or digestibility [ 86 ], have also been reported.…”

Section: Gut Microbiomes and Their Contributions To Their Hostmentioning

confidence: 99%

Impact of Early Weaning on Development of the Swine Gut Microbiome

2023

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Considering that pigs are naturally weaned between 12 and 18 weeks of age, the common practice in the modern swine industry of weaning as early as between two and four weeks of age increases challenges during this transition period. Indeed, young pigs with an immature gut are suddenly separated from the sow, switched from milk to a diet consisting of only solid ingredients, and subjected to a new social hierarchy from mixing multiple litters. From the perspective of host gut development, weaning under these conditions causes a regression in histological structure as well as in digestive and barrier functions. While the gut is the main center of immunity in mature animals, the underdeveloped gut of early weaned pigs has yet to contribute to this function until seven weeks of age. The gut microbiota or microbiome, an essential contributor to the health and nutrition of their animal host, undergoes dramatic alterations during this transition, and this descriptive review aims to present a microbial ecology-based perspective on these events. Indeed, as gut microbial communities are dependent on cross-feeding relationships, the change in substrate availability triggers a cascade of succession events until a stable composition is reached. During this process, the gut microbiota is unstable and prone to dysbiosis, which can devolve into a diseased state. One potential strategy to accelerate maturation of the gut microbiome would be to identify microbial species that are critical to mature swine gut microbiomes, and develop strategies to facilitate their establishment in early post-weaning microbial communities.

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