Correlation between Fine-Needle Aspiration Cytology and Histology for Palpable Breast Masses in a Nigerian Tertiary Health Institution

Daramola, A O; Odubanjo, M O; Obiajulu, F.J.N.; Ikeri, Nzechukwu Zimudo; Banjo, Adekunbiola Aina

doi:10.1155/2015/742573

Cited by 29 publications

(21 citation statements)

References 16 publications

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“…The definition and use of the term “suspicious of malignancy” varies in similar fashion to the term “atypical” and this is reflected in the published range of PPV of a suspicious diagnosis from 60 to 95% [3-6, 8, 12, 14, 15, 70-78]. Two recent studies utilizing the IAC Yokohama System had ROM for a “suspicious of malignancy” diagnosis of 97.1 and 84.6% [16, 17].…”

Section: Category: Suspicious Of Malignancymentioning

confidence: 99%

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The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology

et al. 2019

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The International Academy of Cytology (IAC) gathered together a group of cytopathologists expert in breast cytology who, working with clinicians expert in breast diagnostics and management, have developed the IAC Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy (FNAB) Cytology. The project was initiated with the first cytopathology group meeting in Yokohama at the 2016 International Congress of Cytology. This IAC Yokohama System defines five categories for reporting breast cytology, each with a clear descriptive term for the category, a definition, a risk of malignancy (ROM) and a suggested management algorithm. The key diagnostic cytopathology features of each of the lesions within each category will be presented more fully in a subsequent atlas. The System emphasizes that the crucial requirements for diagnostic breast FNAB cytology are a high standard for the performance of the FNAB and for the making of direct smears, and well-trained experienced cytopathologists to interpret the material. The performance indicators of breast FNAB, including specificity and sensitivity, negative predictive value, positive predictive value and ROM stated in this article have been derived from the recent literature. The current practice of breast FNAB has evolved with the increasing use of ultrasound guidance and rapid on-site evaluation. Two recent publications have shown a range of ROM for the insufficient/inadequate category of 2.6–4.8%, benign 1.4–2.3%, atypical 13–15.7%, suspicious of malignancy 84.6–97.1%, and malignant 99.0–100%. The management algorithm in the System provides options because there are variations in the management of breast lesions using FNAB and core-needle biopsy in those countries utilizing the “triple test” of clinical, imaging, and FNAB assessment, and also variations in the availability of CNB and imaging in low- and middle-income countries. The System will stimulate further discussion and research, particularly in the cytological diagnostic features of specific lesions within each category and in management recommendations. This will lead to continuing improvements in the care of patients with breast lesions and possible modifications to the IAC Yokohama System.

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Section: Category: Suspicious Of Malignancymentioning

confidence: 99%

“…The PPV of a malignant breast FNAB ideally should be 100%, but there is a reported range from 92 to 100% [3-6, 8, 12, 14, 15, 70-78]. Two recent studies utilizing the IAC Yokohama Reporting System had ROM of 100 and 99.0% for the malignant category [16, 17].…”

Section: Category: Malignantmentioning

confidence: 99%

The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology

et al. 2019

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“…The remaining categories were C2 -83.7%, C3-1.4% and C4-2.2% and C5-12.5%. The study by Darmola et al 15 and Ranjan Agarwal 13 et al also reported maximum no of cases in C2 category followed by C5 category. One case which was reported as benign phylloides turned out to be malignant phyllodes in biopsy.…”

Section: Discussionmentioning

confidence: 89%

Spectrum of breast lesions and cyto- histopathological correlation - A retrospective study in a teaching institution in North Malabar

G¹,

Singh²,

Aisabi³

2020

IJPO

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Introduction:Breast carcinoma is the most common malignancy in women. Fine needle aspiration Cytology (FNAC) is an important component of triple approach for diagnosing breast lesions and is highly sensitive, specific, rapid and easy to perform. FNAC has an important role in the preoperative evaluation of breast lesions and deciding treatment. Materials and Methods: The present study was carried out among 350 patients who presented to a tertiary care hospital in North Malabar during a 4 year period from June 2013-June 2017. All cases that presented with breast lump were evaluated with FNAC and the lesions were categorised as C1-C5 as per National Health Service Breast screening programme (NHSBSP) reporting criteria. In 240 cases cytohistopathological correlation was obtained and diagnostic accuracy of FNAC was determined. Aims: To study the spectrum of benign and malignant breast lesions and the efficacy of FNAC as a diagnostic tool by correlating with histopathological findings. Results: Statistical analysis showed that sensitivity of FNAC was 99.46% in benign lesions and 96.2 % in malignant lesions. The specificity and positive predictive value of malignant lesions were 99.46% and 98.07% respectively and that of benign lesions were 96.2% and 98.93% respectively. Conclusions: FNAC serves as a rapid and reliable tool for evaluation of breast lumps with high sensitivity and specificity. However, grey zone lesions of breast which shows atypical / suspicious morphology needs confirmation by biopsy.

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“…Then the tissue was identified as benign or malignant through observation and analysis on cell morphological changes and cell qualitative changes [17]. With FNAC becoming more reliable in diagnosing malignancy, the use of frozensection histology had been reduced by about 80% [18].…”

Section: Breast Cancer Diagnosismentioning

confidence: 99%

Breast Tumor Computer-aided Diagnosis using Self-Validating Cerebellar Model Neural Networks

Guan

Lin

Guo

et al. 2016

APH

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Correlation between Fine-Needle Aspiration Cytology and Histology for Palpable Breast Masses in a Nigerian Tertiary Health Institution

Cited by 29 publications

References 16 publications

The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology

The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology

Spectrum of breast lesions and cyto- histopathological correlation - A retrospective study in a teaching institution in North Malabar

Breast Tumor Computer-aided Diagnosis using Self-Validating Cerebellar Model Neural Networks

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