Correlation between Fluorescein Angiographic Findings and Visual Acuity in Behçet Retinal Vasculitis

Kim, Min; Kwon, Hee Jung; Choi, Eun Young; Kim, Sung Soo; Koh, Hyoung Jun; Lee, Sung Chul

doi:10.3349/ymj.2015.56.4.1087

Cited by 23 publications

(16 citation statements)

References 26 publications

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“…Retinal vascular leakage, optic disc hyperfluorescence, and macular leakage were seen to be associated with a decreased VA [29].…”

Section: Complementary Imaging Modalities and Laboratory Testsmentioning

confidence: 89%

Ocular Manifestations of Behçet’s Disease

Şahlı¹,

Gurbuz-Koz²

2017

Behcet's Disease

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Behçet's disease (BD) is a multisystemic autoimmune inflammatory disorder characterized by oral aphthous lesions, genital ulcerations, iridocyclitis with hypopyon, and skin lesions. While ocular manifestations occur in nearly 50% of the patients with Behçet's disease, ocular involvement is the initial manifestation in only less than 20% of the patients. Ocular Behçet's disease clinically presents iridocyclitis with or without hypopyon, vitritis, retinitis, occlusive retinal vasculitis, and cystoid macular edema. However, anterior uveitis is usually the only initial ocular manifestation; the most common form is panuveitis. The usual course of the disease is characterized by recurrent inflammatory periods. Recurrent inflammatory attacks may result in irreversible damage and significant visual loss. Early and effective treatment is required to prevent ocular morbidity. Recent developments in the treatment of ocular Behçet's disease like biological agents are promising with a rapid effect and high remission rates.

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“…Retinal vascular leakage, optic disc hyperfluorescence, and macular leakage were seen to be associated with a decreased VA [29].…”

Section: Complementary Imaging Modalities and Laboratory Testsmentioning

confidence: 89%

Ocular Manifestations of Behçet’s Disease

Şahlı¹,

Gurbuz-Koz²

2017

Behcet's Disease

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“…6 Other features on FA such as retinal vascular leakage and optic disc hyperfluorescence are also significantly associated with worse initial visual acuity. 7 Hence, at baseline, assessment using FA not only helps in determining disease activity, but also in the prediction of visual recovery following treatment of UME.…”

Section: Fluorescein Angiographymentioning

confidence: 99%

Disease of the Year: Differential Diagnosis of Uveitic Macular Edema

Agarwal

Pichi

Invernizzi

et al. 2018

Ocular Immunology and Inflammation

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Uveitic cystoid macular edema (UME) is an important cause of visual morbidity among patients with both infectious and non-infectious uveitis. UME may be associated in more than 30% cases of active uveitis. However, even patients with minimal features of intraocular inflammation may develop recurrent or chronic UME. Therefore, the evaluation and management of UME in patients with uveitis may be challenging. A number of vitreoretinal pathologies may result in UME and accumulation of fluid in the intra-or subretinal space. These need to be carefully distinguished from each other so that appropriate management can be initiated. All types of uveitis, including anterior uveitis (where the primary site of inflammation is not in the posterior segment) can present with UME. Other conditions such as diabetes, and surgery, can present with macular edema. This index review highlights various differential diagnoses of UME and provides illustrative case examples with multimodal imaging evaluation.

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“…Bei 15 % zeigte sich eine entgegengesetzte Korrelation [11]. Ein vergleichbar diskrepantes Ergebnis fand sich bei 44 % der mit der FAG und der Spectral-Domain-OCT untersuchten Augen mit intermediärer Uveitis [12]. Eine weitere Untersuchung zeigte ebenfalls nur eine moderate Übereinstimmung zwischen der FAG und der OCT: bei 40 % eine Leckage ohne Verdickung in der OCT und eine Netzhautverdickung bei 34 %, aber ohne entsprechende Leckage [10].…”

Section: Untersuchungstechnikenunclassified

Makulaödem bei Uveitis – Steroide oder VEGF-Inhibitoren?

Heinz

Heiligenhaus

2017

Klin Monatsbl Augenheilkd

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Macular edema in uveitis patients is certainly the most frequent complication leading to a permanent and irreversible reduction in vision during the course of the disease. Thanks to optical coherence tomography (OCT) technology and fluorescein angiography (FAG), significantly more macular edemas are detected. Macular edema can be found in various uveitis varieties and can show different clinical patterns. All macular edema should be treated. Macular edema with active inflammation usually reacts very well to general uveitis treatment. In the case of eyes without visible inflammation, however, the response to such therapy is usually less effective. According to the latest treatment recommendations, dexamethasone implants should be used as the first intravitreal therapy. Vascular endothelial growth factor inhibitors (VEGF inhibitors) are second-line treatment regimens. The choice of therapy is, therefore, primarily based on the degree of inflammation and the individual complications, such as glaucoma, lens situation or previous increase in IOP after steroid administration. These individual complications may allow using VEGF inhibitors as first line treatment. An improvement in the macular edema can be achieved with both groups of active substances.

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Correlation between Fluorescein Angiographic Findings and Visual Acuity in Behçet Retinal Vasculitis

Cited by 23 publications

References 26 publications

Ocular Manifestations of Behçet’s Disease

Ocular Manifestations of Behçet’s Disease

Disease of the Year: Differential Diagnosis of Uveitic Macular Edema

Makulaödem bei Uveitis – Steroide oder VEGF-Inhibitoren?

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