Correlation between glycaemic state and tooth mobility in periodontal patients

Abstract

Objective: To evaluate the association of tooth mobility with blood glucose levels and control in patients with periodontitisMethodology: The study was conducted at the department of Oral Medicine, Ziauddin Dental Hospital, Karachi. The study design was cross-sectional. The duration of this study was of 6 months, between December 2018 and May 2019. The study population involved 348 patients with chronic periodontitis. After recording demographic details and dental charting, tooth mobility scores were correlated with gingival crevicular blood glucose, finger capillary blood glucose and glycosylated hemoglobin levels by Pearson’s correlation. Linear regression was applied to assess the inter-relation between variables.Results: The mean age of individuals who participated in this study was 43+/-10.4 years. The average number of teeth present in patients with glucose levels <180mg/dl was 25.5+/-2.5 compared to 23.2+/-2.9 in individuals with glucose values of >200mg/dl. A moderate positive correlation (r=0.658) was seen between gingival crevicular blood glucose levels and tooth mobility. Finger capillary blood glucose levels also showed good correlation (R=0.653) with tooth mobility scores. HbA1c scores showed a strong positive correlation(R=0.733). Linear regression confirmed increased HbA1c as a risk factor for tooth mobility (R2=0.524, p value= 0.000).Conclusion: Tooth mobility and glycaemic levels are strongly interrelated. This study provides evidence that poor glycaemic control may contribute to the etiology of tooth mobility in patients with periodontitis. Continuous...

The reliability of using gingival crevicular blood to measure blood glucose and hba1c levels in the dental setting: a systematic review and meta-analysis

“…The included articles were published between 1993 and 2023. The majority of the literature is from India with 13 studies [ 13 , 25 – 35 ], two from Kuwait [ 36 , 37 ] and the USA [ 38 , 39 ], and one from China [ 14 ], Italy [ 12 ], Pakistan [ 40 ], Jordan [ 41 ], Germany [ 42 ] and Iran [ 43 ] respectively. All in all, the studies included 1680 mostly middle-aged patients with an average age of 44.4 and with a roughly equal distribution of sex with slightly more females (51%).…”

“…16 studies have reported their outcomes in mg/dl while two in mmol/l which were converted to mg/dl by the authors. The highest and lowest mean values recorded from GCB was 243.27 and 156.07 mg/dl in the DM group and 118.76 and 90.08 mg/dl in the non-DM group respectively [ 12 , 25 – 35 , 37 , 40 , 41 , 43 – 45 ]. Two of the studies have found statistically significant differences between GCB and CB values ( p = 0.001) [ 33 , 37 ].…”

Clinical observation of Porcine Collagen Membrane + artificial Bovine Bone Granules Guided tissue regeneration combined with Autologous CGF in the treatment of severe periodontitis bone defect

“…As periodontitis develops, it will be accompanied by alveolar bone destruction and resorption and loss of periodontal attachment, which will further lead to tooth loosening and even loss. 12 Severe periodontitis bone defect is a formidable challenge for periodontal bone repair. Traditionally, periodontal replantation has been used to facilitate the rapid healing of bone defects and the formation of new periodontal attachments.…”