Correlation between NRS-2002 combined with GLIM criteria and preoperative sarcopenia in patients with gastrointestinal malignancies：A prospective cohort study

Abstract

Background & Purpose Since the Global Leadership Initiative on Malnutrition (GLIM) criteria are based on expert consensus recommendations, more clinical practice is needed to be validated. Currently, there is a lack of Nutritional Risk Screening 2002(NRS-2002) combined with the GLIM used in the diagnosis of muscle loss and malnutrition. The aim is to investigate the correlation between NRS-2002 in combination with The GLIM criteria in patients with gastrointestinal malignancies with muscle loss (sarcopenia). Methods In this study, we selected 210 patients with gastrointestinal malignant tumors from June 2022 to July 2023 from X Hospital. The nutritional status of the patients was assessed using the NRS-2002 and the GLIM diagnostic criteria. Patients were categorized as nutritionally normal, at nutritional risk, moderately malnourished, or severely malnourished based on the NRS-2002 in conjunction with the GLIM criteria. Results The prevalence of sarcopenia differed among various nutritional status groups( p < 0.01). In the moderately malnourished group and the severely malnourished group, the prevalence of sarcopenia was 36% and 83%, respectively. A positive correlation was observed between malnourishment and the presence of sarcopenia, as indicated by NRS-2002 (p < 0.001). Results from binary logistic regression analysis revealed that gender, height, ASMI, nutritional risk, and malnutrition were all risk factors for the development of sarcopenia (p < 0.05). Conclusion The prevalence of preoperative sarcopenia in patients with gastrointestinal malignancies is high, and there is a correlation between the NRS-2002 combined with GLIM criteria and sarcopenia in gastrointestinal malignancies.