Correlation between Osteopontin Promoter Gene and Fresh Semen Quality in Friesian Holstein Dairy Cows

Background; Herbal medicine is the world's oldest type of healthcare. Hibiscus rosa flower and leave extracts are used as natural remedies to treat various diseases, and as a reversible antifertility for males. Aim and objectives; this study aimed to investigate the effectiveness of nanoparticles to improve the impact of Hibiscus rosa flower extract as an anti-fertility substance. Animals and methods; twenty male albino rats were divided into five groups: G1 (-ve control): treated with normal saline (0.2 ml per day), G2 (+ve control): treated with nanoparticles (300mg empty liposome per day), G3: treated with flower extract nanoparticles (100mg/kg per day), G4: treated with flower extract nanoparticles (200mg/kg per day), and last group G5: treated with flower extract nanoparticles (300mg/kg per day). Sperm function tests (sperm concentration, sperm motility percent, and sperm viability percent) were estimated after the treatment in the five groups after 55 days of daily treatment. Besides, the diagnosis of compounds in the extracts of palmic acid “ethyl ester”, ascorbic acid, 9-octadecenoic acid “methyl ester”, methyl stearate, oleic acid, 9,12-octadecadienoic acid, eicosane, heptadecane, 1-(1,5-dimethyl hexyl, fumaric acid, butanediol, stigmasterol, and beta-sitosterol, was performed using gas chromatography-mass (GC/MS) method.

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“…And analgesic [11]. Besides, this plant has hypolipidemic and anti-diabetic effects [12][13][14]. Anti-parasitic effect [15].…”

Section: Introductionmentioning

confidence: 99%

Effect of Hibiscus Rosa nanoparticles on sperm parameters of male albino rats

Kareem¹,

Alhady²,

Mansour³

2022

ijhs

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The Impact of Human Genome on Interindividual variability in Drug Response

Swamini,

Nandini,

Mankar

2024

RJPPD

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Pharmacogenomics is an important aspects of clinical genomics i.e an increasingly large number of patients it have extremely broad cast application a pharmacogenomics has evolved from early Pharmacogenetic studies of candidate gene often genes. Pharmacogenomics has the potential to mitigate adverse drug reaction and optimise pharmaco therapy in individual it has the potential to revolutionize the practice of medicine and promises to in an area of personised medicine in which drug and drug combination optimised for each Individual unique genetic makeup. It is well recognised that most medications exhibit wide interpatient variability in their efficacy and toxicity. For many medications interindividual differences in polymorphism of incoding genes in drug metabolising enzymes drug transporter, Target drugs eg. receptors, enzymes. The ultimate goal is to provide new strategies for optimising drug therapy based on each patient genetic determinants of drug efficacy and toxicity.

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Correlation between Osteopontin Promoter Gene and Fresh Semen Quality in Friesian Holstein Dairy Cows

Cited by 2 publications

References 6 publications

Effect of Hibiscus Rosa nanoparticles on sperm parameters of male albino rats

Effect of Hibiscus Rosa nanoparticles on sperm parameters of male albino rats

The Impact of Human Genome on Interindividual variability in Drug Response

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