2017
DOI: 10.1111/vox.12598
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Correlation between plasma fibrinogen and FIBTEM thromboelastometry during liver transplantation: a comprehensive assessment

Abstract: FIBTEM MCF is not a good indicator of plasma fibrinogen values after graft reperfusion. FIBTEM MCF >8 mm during the LT procedure is associated with less RBC transfusion. FIBTEM MCF values over 10 mm could lead to unnecessary fibrinogen administration.

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Cited by 14 publications
(5 citation statements)
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“…Both FF-TEG and ROTEM MCF FIBEM have been shown to correlate well with fibrinogen level in the liver transplant setting, 31,32 except in severe hypofibrinogenemia, particularly after graft reperfusion, which does not appear to be detected well by VETs. 27,32,48 ROTEM parameters MCF EXTEM and MCF INTEM have also been shown to correlate well with platelet count intraoperatively. 31 Importantly, for real-time decision-making, several ROTEM parameters (A5, A10, MCF) have also been shown to correlate with platelet and fibrinogen counts.…”
Section: Liver Transplantmentioning
confidence: 86%
“…Both FF-TEG and ROTEM MCF FIBEM have been shown to correlate well with fibrinogen level in the liver transplant setting, 31,32 except in severe hypofibrinogenemia, particularly after graft reperfusion, which does not appear to be detected well by VETs. 27,32,48 ROTEM parameters MCF EXTEM and MCF INTEM have also been shown to correlate well with platelet count intraoperatively. 31 Importantly, for real-time decision-making, several ROTEM parameters (A5, A10, MCF) have also been shown to correlate with platelet and fibrinogen counts.…”
Section: Liver Transplantmentioning
confidence: 86%
“…More recently, A10FIBTEM.á<.á8.ámm and A10EXTEM.á<.á35.ámm have been found to predict intraoperative bleeding. 34 , 35 …”
Section: Discussionmentioning
confidence: 99%
“…48 Similar to that, in major liver resections where alterations in coagulation are complex and highly dependent on the pre-existing liver dysfunction, the presence of malignancy, extent of intra-operative blood loss, surgical technique, ischemia-reperfusion injury as well as the volume of the liver remnant post resection, 49 ROTEM testing can significantly aid in predicting bleeding risk when compared with the standard coagulation testing. 15,29,50 Several limitations need to be considered when interpreting the results of the present systematic review. There was a large heterogeneity in patient characteristics and indications for resection (benign vs malignant disease) among individuals analyzed in the present review.…”
Section: Discussionmentioning
confidence: 99%