Correlation between porosity and dissolution rate constants for disintegrating tablets

Cruaud, Odile; Duchêne, Dominique; Puisieux, F.; Carstensen, J.T.

doi:10.1002/jps.2600690539

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Cited by 7 publications

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“…This relationship dictates the rate of solvent penetration into a capillary bed and thus has a direct impact on disintegration. [22][23][24] On the basis of the eqs 1-3, for a given substrate with constant ␥ SV , wetting will be influenced by the interfacial tensions at the solid-liquid and liquidvapor interfaces. 18,19 It is clear that the processes associated with surfactant wetting are important in the dissolution of dosage forms.…”

Section: Introductionmentioning

confidence: 99%