Correlation between CT‐based measured renal volumes and nuclear‐renography‐based split renal function in living kidney donors. Clinical diagnostic utility and practice patterns

Abstract

CT-based volume measurements in living donor imaging have sufficient correlation with nuclear-based SRF. Selective use of nuclear-scan-based SRF allows careful selection for donor nephrectomy.

CT volumetry is superior to nuclear renography for prediction of residual kidney function in living donors

“…Several studies have previously compared CT‐based techniques with nuclear renography to estimate split kidney function and have shown a high correlation between results, suggesting the feasibility of using CT techniques in this fashion . The two most common types of CT‐based studies are CT volumetry and CT‐GFR.…”

“…Other studies have calculated split kidney function using algorithms that quantify and compare kidney enhancement as a function of time after intravenous contrast injection . CT‐based studies have shown a high level of concordance with nuclear renography for determining split kidney function and suggest the feasibility of performing a comprehensive evaluation of live donor candidates using solely CT …”

Editorial Comment from Dr Teishima and Dr Matsubara to Clinical application of calculated split renal volume using computed tomography‐based renal volumetry after partial nephrectomy: Correlation with technetium‐99m dimercaptosuccinic acid renal scan data

“…addressed the clinical impact of split renal volume (SRV) calculated on the basis of the findings of computed tomography (CT) used to evaluate renal function in patients with renal cell cancer who underwent partial nephrectomy . Previous studies have shown the correlation between renal parenchymal volume determined by CT‐based renal volumetry and loss of estimated glomerular filtration rate, and other studies of living kidney donors have compared the findings of CT‐based renal volumetry and those of nuclear renal scans . On the basis of the results of these studies, the present study shows the possible usefulness of CT‐based volumetry along with nuclear renal scans for estimating split renal functions after nephron‐sparing surgery.…”

Clinical application of calculated split renal volume using computed tomography‐based renal volumetry after partial nephrectomy: Correlation with technetium‐99m dimercaptosuccinic acid renal scan data

“…According to these reports, there was a significant correlation between mean percent RPV loss and the mean percent eGFR loss ( r = 0.52–0.79). However, although several reports have compared CT‐based volumetry with nuclear renal scan in living kidney donors, there is no such report for nephron‐sparing surgery . As nuclear renal scans provide more accurate information about functional renal parenchyma, it is noteworthy that a stronger significant correlation was found between CT‐based volumetry and nuclear renal scan.…”

“…Recent studies have compared SRV estimated by CT datasets with SRF estimated by nuclear renal scan in living kidney donors for renal transplantation . These studies have shown a significant correlation between SRF and SRV estimated by the two methods ( r = 0.46–0.93).…”