Correlation between the Glasgow-Blatchford score, shock index, and Forrest classification in patients with peptic ulcer bleeding

Hong, Yang; Pan, Chen; Liu, Q I; Wang, Yan; Liu, Zhe; Chen, Xian; Ji, Lei

doi:10.3906/sag-1906-154

Cited by 3 publications

(2 citation statements)

References 30 publications

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“…One type focuses on assessing the prognosis of patients with liver cirrhosis, including the Model for End-Stage Liver Disease (MELD), Child-Pugh score, and MELD-Na, which add serum sodium to the MELD system ( 10 , 11 ). The other type evaluates acute upper gastrointestinal bleeding, including the Glasgow Blatchford, Rockall, and AIMS65 ( 12 ). Bai et al recently proposed the cirrhosis acute gastrointestinal bleeding (CAGIB) system, which includes diabetes (DB), hepatocellular carcinoma (HCC), bilirubin, albumin, alanine aminotransferase (ALT), and creatinine ( 13 ).…”

Section: Introductionmentioning

confidence: 99%

A New Scoring System for Predicting In-hospital Death in Patients Having Liver Cirrhosis With Esophageal Varices

Zhang

Wang

et al. 2021

Front. Med.

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Introduction: Liver cirrhosis is caused by the development of various acute and chronic liver diseases. Esophageal varices is a common and serious complication of liver cirrhosis during decompensation. Despite the development of various treatments, the prognosis for liver cirrhosis with esophageal varices (LCEV) remains poor. We aimed to establish and validate a nomogram for predicting in-hospital death in LCEV patients.Methods: Data on LCEV patients were extracted from the Medical Information Mart for Intensive Care III and IV (MIMIC-III and MIMIC-IV) database. The patients from MIMIC-III were randomly divided into training and validation cohorts. Training cohort was used for establishing the model, validation and MIMIC-IV cohorts were used for validation. The independent prognostic factors for LCEV patients were determined using the least absolute shrinkage and selection operator (LASSO) method and forward stepwise logistic regression. We then constructed a nomogram to predict the in-hospital death of LCEV patients. Multiple indicators were used to validate the nomogram, including the area under the receiver operating characteristic curve (AUC), calibration curve, Hosmer-Lemeshow test, integrated discrimination improvement (IDI), net reclassification index (NRI), and decision curve analysis (DCA).Results: Nine independent prognostic factors were identified by using LASSO and stepwise regressions: age, Elixhauser score, anion gap, sodium, albumin, bilirubin, international normalized ratio, vasopressor use, and bleeding. The nomogram was then constructed and validated. The AUC value of the nomogram was 0.867 (95% CI = 0.832–0.904) in the training cohort, 0.846 (95% CI = 0.790–0.896) in the validation cohort and 0.840 (95% CI = 0.807–0.872) in the MIMIC-IV cohort. High AUC values indicated the good discriminative ability of the nomogram, while the calibration curves and the Hosmer-Lemeshow test results demonstrated that the nomogram was well-calibrated. Improvements in NRI and IDI values suggested that our nomogram was superior to MELD-Na, CAGIB, and OASIS scoring system. DCA curves indicated that the nomogram had good value in clinical applications.Conclusion: We have established the first prognostic nomogram for predicting the in-hospital death of LCEV patients. The nomogram is easy to use, performs well, and can be used to guide clinical practice, but further external prospective validation is still required.

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Section: Introductionmentioning

confidence: 99%

A New Scoring System for Predicting In-hospital Death in Patients Having Liver Cirrhosis With Esophageal Varices

Zhang

Wang

et al. 2021

Front. Med.

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“…The imperfection of prognostic scales is one of the reasons for high morbidity. The most common scales are Rockall, GlasgowBlatchford, Baylor, Cedars-Sinai, AIMS65, PNED [ 7 - 10 ]. However, according to some authors, more accurate scales are needed [ 8 ], and this is why they suggest using additional predictive criteria [ 8 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Justification of Genetic Factors for Predicting the Risk of Acute Bleeding in Peptic Ulcer Disease

et al. 2020

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Specific Diagnoses and Management Principles of the Upper Digestive Canal

SEZGIN

Karcıoğlu

YENİOCAK³

et al. 2022

Abdominal Pain: Essential Diagnosis and Management in Acute Medicine

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Acute abdominal conditions which frequently necessitate emergency interventions and/or surgery include visceral perforations i.e., gastric and duodenal ulcer, bleeding and rarely, ingested foreign bodies causing tissue damage, e.g., button batteries. However, the differential diagnosis (DD) of patients presenting with acute abdominal pain is much broader than this, including many benign conditions as well. Acute gastroenteritis, acute gastritis and peptic ulcer disease are benign and mostly temporary diseases which may be relieved with simple treatments and follow-up. Gastrointestinal bleeding (with or without esophageal varices) may cause hemorrhagic shock unless expedient management is pursued. Ingested foreign bodies can constitute emergency conditions with tissue damage, especially when lodged in a specific site. The most important thing about button batteries is the prevention of their ingestion. Complications increase in direct proportion to time wasted.

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Correlation between the Glasgow-Blatchford score, shock index, and Forrest classification in patients with peptic ulcer bleeding

Cited by 3 publications

References 30 publications

A New Scoring System for Predicting In-hospital Death in Patients Having Liver Cirrhosis With Esophageal Varices

A New Scoring System for Predicting In-hospital Death in Patients Having Liver Cirrhosis With Esophageal Varices

Justification of Genetic Factors for Predicting the Risk of Acute Bleeding in Peptic Ulcer Disease

Specific Diagnoses and Management Principles of the Upper Digestive Canal

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