Correlation of estriol excretion patterns of pregnant women with subsequent development of their children

Biochemical Tests for the Assessment of Feto-Placental Function

“…In a group of 38 infants delivered prematurely following low oestrogen excretion, however, only four died in the neonatal period, whereas in a comparable group of 21 patients whose deliveries were not induced 14 infants died soon after birth (Heys et al, 1968). With regard to neurological handicaps Greene et al (1969), in a careful study with suitable control patients, showed that delivery after subnormal oestrogen excretion did not predispose to developmental problems in comparison 88 with infants matched for birth weight and gestation period.…”

Estrogen screening in evaluation of fetal outcome and infant’s development

“…In some previous of cost-benefit-calculations an Es-screening of studies with 14 or 34 patients, some connection every pregnant woman cannot be recombetween low UE and psychomotoric develop-mended. In pregnancies at risk, however, serial ment disorders have been reported [14,29,30]. Es determinations once weekly in addition to TROLLE et al [28] published follow-up studies on ultrasound and nonstress testing allow a better 110 children (8 to 14 years old) with previously prognostication of fetal well-being.…”

Review article

“…The subsequent development of babies born after low estrogen values in pregnancy might be expected to be at increased risk. From the small number of cases studied there is an unproven Suggestion that neurological development was impaired in some when urinary estrogen values had been chronically low, but not when only an occasional value was low or there had been an acute terminal fall [30, 46,134]. WALLACE and MICHDE [130] were worried 10 years ago that action to save fetuses associated with low estrogen values would result in an unwelcome proportion of damaged or deformed babies, but this has not been substantiated.…”