Susceptibilities of Staphylococcus aureus strains derived from furuncle and bullous impetigo to Ampicillin, Cephalexin, Erythromycin, Tetracycline and Chloramphenicol were studied by examining their minimum inhibitory concentrations. Susceptibilities to every antibiotic studied were lower among the furuncle group than bullous impetigo group. This result is considered to be due to differences in the types of strains causing the two pyodermas. It was also indicated in this study that the susceptibilities to the antibiotics (Ampicillin, Cephalexin, Erythromycin and Tetracycline) which have been used in greater amounts were higher than that to the antibiotic (Chloramphenicol) which has been used in lesser ones.