Correlations Between Neoadjuvant Treatment, Anemia, and Perioperative Complications in Patients Undergoing Esophagectomy for Cancer

Meta-analysis of the association between preoperative anaemia and mortality after surgery

“…Characteristics of the included studies are summarized in Table . A total of 949 445 patients were included, and all 24 studies reported the primary outcome of 30‐day or in‐hospital mortality.…”

“…However, stroke and myocardial infarction were reported as an outcome only in studies of patients undergoing cardiac surgery ( Table ). A haemoglobin definition was used in 17 studies, a haematocrit definition in six studies, and both definitions were used in one study. Definitions of anaemia ranged from a haemoglobin concentration of 11 to 12 g/dl or a haematocrit of 30–39 per cent for female patients, and from 11 to 14 g/dl or 30–39 per cent respectively for male patients.…”

Nutrition in peri-operative esophageal cancer management

“…Preoperative anemia is common in esophageal cancer and is a risk factor in itself for a worse clinical outcome, as well as a strong predisposing factor for perioperative blood transfusion, which in turn increases morbidity, mortality, and costs [70][71][72]. Detection, diagnosis, and proper treatment of anemia are central in the concept of preoperative blood management in surgical patients [70].…”

Enhanced Recovery for Esophagectomy

“…49,50 Therapeutic options include iron and erythropoietin (EPO). 49,50 Therapeutic options include iron and erythropoietin (EPO).…”