Correlations between three-dimensional speckle-tracking echocardiography-derived left atrial functional parameters and aortic stiffness in healthy subjects – Results from the MAGYAR-Healthy Study

Nemes, Attila; Piros, GyÁ; Domsik, Péter; Kalapos, Anita; Lengyel, C; Orosz, Andrea; Forster, Tamás

doi:10.1556/036.102.2015.2.10

Cited by 4 publications

(4 citation statements)

References 22 publications

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“…Over LV volumetric measurements, several LV functional parameters including different uni-(RS, LS, and CS) and multidirectional (AS and 3DS) strain parameters could be calculated together with parameters of LV rotational mechanics using the same LV-3D model. At present, limited numbers of papers are available, in which relationships between 3DSTE-derived left heart deformation parameters and aortic elasticity are examined (12,13). Correlations could be detected between echocardiographic aortic elastic properties and LV rotation and twist (10,12) and left atrial functional features (13) in healthy subjects.…”

Section: Discussionmentioning

confidence: 99%

“…At present, limited numbers of papers are available, in which relationships between 3DSTE-derived left heart deformation parameters and aortic elasticity are examined (12,13). Correlations could be detected between echocardiographic aortic elastic properties and LV rotation and twist (10,12) and left atrial functional features (13) in healthy subjects. This methodology could help in widening our knowledge in understanding arterial-ventricular coupling.…”

Section: Discussionmentioning

confidence: 99%

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Is there a relationship between increased aortic stiffness and segmental left ventricular deformation in elite athletes? (Insights from the MAGYAR-Sport Study)

et al. 2017

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Introduction Myocardial contractility of the left ventricle (LV) is related to arterial distensibility. Sport activity is frequently associated with changes in both LV and arterial functions. This study aimed to find correlations between three-dimensional speckle-tracking echocardiography-derived segmental LV deformation parameters and echocardiographically assessed aortic stiffness index (ASI) in athletes. This study comprised 26 young elite athletes (mean age: 26.7 ± 8.4 years, nine men). Results Among segmental circumferential strains (CSs), only that of apical anterior (r = 0.40, p = 0.05), septal (r = 0.47, p = 0.01), inferior (r = 0.59, p = 0.001), lateral (r = 0.44, p < 0.05), and midventricular anteroseptal (r = 0.44, p < 0.05) segments correlated with ASI, whereas LV-CS of the midventricular anterior segment showed a correlation tendency. Only longitudinal strain of basal anteroseptal (r = -0.46, p < 0.05) and inferoseptal (r = -0.57, p < 0.01) segments showed correlations with ASI, whereas that of the basal anterior segment had only a tendency to correlate. Some segmental multidirectional strains also correlated with ASI. Conclusions Correlations could be demonstrated between increased aortic stiffness and circular function of the apical and midventricular LV fibers and longitudinal motion of the basal septum and LV anterior wall (part of LV outflow tract) in maintaining circulation in the elite athletes.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Is there a relationship between increased aortic stiffness and segmental left ventricular deformation in elite athletes? (Insights from the MAGYAR-Sport Study)

et al. 2017

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“…Recently, Nemes’ et al, reported that most of left atrial functional indices including atrial booster pump, reservoir, and conduit functions, were correlated with aortic elastic properties. Furthermore, they found a significant relation between echocardiographic aortic elastic properties and all the LA phasic functions by 3DSTE‐derived volume‐based and strain parameters.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, left ventricular (LV) remodeling is a powerful determinant of left atrial (LA) size, consequently aortic stiffness could influence left atrial remodeling. [32][33][34] Recently, Nemes' et al, 35 reported that most of left atrial functional indices including atrial booster pump, reservoir, and conduit functions, were correlated with aortic elastic properties.…”

Section: Discussionmentioning

confidence: 99%

Association between left atrial stiffness and aortic plaque thickness in hypertensive patients with stroke

et al. 2018

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Objective Our aim was to investigate the relation between left atrial stiffness (LASt) and thoracic aortic plaque thickness in hypertensive patients with stroke. Method A total of 97 hypertensive patients were recruited (age: 59.2 ± 7.5 years), including 56 consecutive patients with undefined stroke and 41 age‐matched hypertensive patients without stroke. Left atrial strain and stiffness were measured using speckle tracking echo. Thoracic aortic plaque detection and evaluation was performed using transesophageal echocardiography. Results Hypertensive patients with stroke, when compared with those without stroke, had a significantly higher LASt value (P < .001). The percentage of plaque 1–4 mm thickness were comparable in both groups (23.2% vs 21.9%; P > .05). While the percentage of plaque ≥4 mm thickness was much higher in hypertensive patients with stroke (71.4% vs 4.9%; P < .001). LASt was considerably increased in hypertensive group with paroxysmal atrial fibrillation (PAF) when compared to hypertensive group without PAF (P < .01). A significant positive correlation was found between the LASt and plaque thickness (P < .001). Multivariate analysis showed that LASt was the strongest independent predictor for ≥4 mm aortic plaque thickness (Hazard ratio = 6.153; P < .001). With receiver operating characteristic (ROC) curve analysis, LASt > 0.63 was the best cutoff value in predicting aortic plaque thickness ≥ 4 mm. Conclusion Left atrial stiffness was significantly associated with aortic plaque thickness ≥ 4 mm, in hypertensive patients with stroke. These finding prevailed the importance of LASt in risk stratification of hypertension.

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The Progress of Advanced Ultrasonography in Assessing Aortic Stiffness and the Application Discrepancy between Humans and Rodents

Xie

Qiu

2021

Diagnostics

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: Aortic stiffening is a fundamental pathological alteration of atherosclerosis and other various aging-associated vascular diseases, and it is also an independent risk factor of cardiovascular morbidity and mortality. Ultrasonography is a critical non-invasive method widely used in assessing aortic structure, function, and hemodynamics in humans, playing a crucial role in predicting the pathogenesis and adverse outcomes of vascular diseases. However, its applications in rodent models remain relatively limited, hindering the progress of the research. Here, we summarized the progress of the advanced ultrasonographic techniques applied in evaluating aortic stiffness. With multiple illustrative images, we mainly characterized various ultrasound techniques in assessing aortic stiffness based on the alterations of aortic structure, hemodynamics, and tissue motion. We also discussed the discrepancy of their applications in humans and rodents and explored the potential optimized strategies in the experimental research with animal models. This updated information would help to better understand the nature of ultrasound techniques and provide a valuable prospect for their applications in assessing aortic stiffness in basic science research, particularly with small animals.

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Correlations between three-dimensional speckle-tracking echocardiography-derived left atrial functional parameters and aortic stiffness in healthy subjects – Results from the MAGYAR-Healthy Study

Cited by 4 publications

References 22 publications

Is there a relationship between increased aortic stiffness and segmental left ventricular deformation in elite athletes? (Insights from the MAGYAR-Sport Study)

Is there a relationship between increased aortic stiffness and segmental left ventricular deformation in elite athletes? (Insights from the MAGYAR-Sport Study)

Association between left atrial stiffness and aortic plaque thickness in hypertensive patients with stroke

The Progress of Advanced Ultrasonography in Assessing Aortic Stiffness and the Application Discrepancy between Humans and Rodents

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