“…Therefore, it is often used as a bone graft substitute in biomedical clinics [ 7 ]. Different forms of apatite with different sizes and shapes (e.g., flakes, spheres, needles, and rods) have been fabricated using wet and dry synthesis strategies [ 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. HA can be synthesized by a precipitation method [ 8 , 9 ], sol-gel method [ 10 , 11 ], hydrothermal method [ 8 , 9 , 10 ] and microwave-assisted synthesis method [ 15 , 16 ], or it can be directly extracted from biological resources [ 17 , 18 , 19 ].…”