Corrigendum. ART in Europe, 2015: results generated from European registries by ESHRE

Geyter, Ch. De; Calhaz‐Jorge, Carlos; Kupka, M.; Wyns, Christine; Mocanu, Edgar; Motrenko, T; Scaravelli, G.; Smeenk, J.M.J.; Vidaković, S; Goossens, V.

doi:10.1093/hropen/hoaa038

Cited by 137 publications

(101 citation statements)

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“…The goal of ovarian stimulation is the collection of multiple dominant follicles in an effort to compensate for the inefficiencies of embryology culture, embryo selection, thus improving chances for successful conception in IVF [129]. The definition of poor ovarian response (POR) should be understood as an essential inability of woman's ovaries to properly react to the selected stimulation [130]. At least two of the following three features must be present for the POR to be diagnosed: 1) advanced maternal age (≥40 years), or any other risk factor for POR; 2) a previous POR (≤3 oocytes with a conventional stimulation protocol); 3) an abnormal ovarian reserve test (antral follicle count: 5-7 follicles, or Anti-Mullerian hormone 0.5-1.1 ng/ml) [131][132][133].…”

Section: Ovarian Response To Stimulationmentioning

confidence: 99%

Reasons and Mechanisms of Recurrent Failed Implantation in IVF

Fodina¹,

Dudorova²,

Ērenpreiss³

2021

Infertility and Assisted Reproduction

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Recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) are serious problems in IVF and ICSI cycles. Different factors are showed to be responsible for these clinical challenges – such as paternal, maternal, embryonic, immunological, infectious, hormonal, and others. In this chapter we have tried to review the available data on reasons for the RIF, and systematize them into: 1) uterine factors; 2) embryo factors; 3) immunological factors; 4) other factors. Interplay between all these factors play a role in RIF, and further investigations are needed to elucidate their significance and interactions – in order to elaborate more definite suggestions or guidelines for the clinicians dealing with artificial reproductive techniques and facing RPL and RIF.

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Section: Ovarian Response To Stimulationmentioning

confidence: 99%

Reasons and Mechanisms of Recurrent Failed Implantation in IVF

Fodina¹,

Dudorova²,

Ērenpreiss³

2021

Infertility and Assisted Reproduction

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“…19 Likewise, the European Society of Human Reproduction and Embryology has recorded an implantation rate of 29% and live-birth rate of 22% from 508,433 cycles documented in 2014. 20 Thus, implantation failure (IF), designated as either absence of hCG rise or absence of a gestational sac in those for whom an hCG rise was documented, 17 remains a challenge in ART.…”

Section: Implantation Failurementioning

confidence: 99%

The Pathophysiology of Hypercoagulability and Infertility

Malinowski

2021

Semin Reprod Med

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Alongside an interplay of a multitude of factors, attainment of a favorable pregnancy outcome is predicated on successful implantation, which in itself is a complex process anchored by balanced interchange with the hemostatic system. Among other etiologies, failure of implantation can result in infertility, and lead affected couples to consider assisted reproductive technology (ART) in an effort to fulfill their desire for procreation. Given the critical role of the hemostatic system in the process of implantation, documentation of a hypercoagulable state during controlled ovarian stimulation in the context of in vitro fertilization, as well as the potential association of its derangement in the setting of thrombophilia, with infertility, ART, ovarian hyperstimulation syndrome, and failure of implantation are explored. Additionally, current evidence addressing the relationship between ART and thromboembolism is examined, as is the role of therapy with heparin and aspirin to decrease thrombotic risk and improve ART-related pregnancy outcomes. Evidence-based recommendations from relevant professional societies are summarized.

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“…The worldwide shift towards frozen embryo transfer (FET) has accelerated, as more frozen embryos are currently available per patient for future use [1]. Multiple factors contributed to this change, beginning primarily with improved incubators and changes in the mode of embryo preservation towards vitrification, which improved the survival rate and quality of the thawed embryos [2].…”

Section: Introductionmentioning

confidence: 99%

Ovulatory-Based FET Cycles May Achieve Higher Pregnancy Rates in the General Population and among Anovulatory Women

Aslih

Dorzia

Atzmon

et al. 2021

JCM

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This study evaluated which endometrial preparation protocol in frozen embryo transfer (FET) cycles provides the best results for polycystic ovarian syndrome (PCOS) patients and the general population. This retrospective study of 634 FET cycles was conducted 2016–2018. Cycles were divided into Group A: Artificial endometrial preparations for FET (aFET; n = 348), Group B: Ovulatory cycle (n = 286) to compare two methods of endometrial preparation for FET. Artificial endometrial preparation with exogenous estrogen and progesterone versus natural ovulation cycles, modified natural cycles using hCG for the final triggering and letrozole-induced ovulation with hCG. Anovulatory patients were analyzed separately. Anovulatory PCOS patients had significantly higher pregnancy rates with letrozole treatment compared with aFET cycles (44% vs. 22.5%; p = 0.044). For the entire cohort, ovulatory cycles and aFET were similar in terms of patient characteristics, demographics, infertility causes, treatment protocols and number of embryos transferred. Although the mean ESHRE score of the transferred embryos was higher in the aFET group, we found higher clinical pregnancy rate in the ovulatory cycle FET (41.3% vs. 27.3%, p < 0.0001). A better pregnancy rate was found after ovulatory cycle FET. In the ovulatory cycles, the outcome of letrozole-induced and non-induced cycles were comparable. PCOS patients, as well as the general population, may benefit from ovulation induced FET cycles, with significantly better outcomes in FET in ovulatory cycles.

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Corrigendum. ART in Europe, 2015: results generated from European registries by ESHRE

Cited by 137 publications

References 0 publications

Reasons and Mechanisms of Recurrent Failed Implantation in IVF

Reasons and Mechanisms of Recurrent Failed Implantation in IVF

The Pathophysiology of Hypercoagulability and Infertility

Ovulatory-Based FET Cycles May Achieve Higher Pregnancy Rates in the General Population and among Anovulatory Women

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