Corrigendum: TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency

Abstract

First, we mistakenly incorporated two sentences in the first paragraph of the Introduction from an article by Venables et al. (2013). These two sentences have been deleted: "For example, different isoforms of Foxp1 produced from ESC-specific AS have differential effects on the induction of key pluripotency genes such as OCT4 and NANOG (Gabut et al. 2011). Similarly, alternative splice forms of DNMT3B are specific to stem cells, implying that layered and integrated regulation of gene expression occurs at the levels of transcription and splicing (Gopalakrishna-Pillai and Iverson 2011)." This text has been replaced as follows: "For example, different isoforms of Foxp1 and Oct4, which are important transcription factors that function in determining stem cell identities, are produced by ESC-specific AS, and this controls their transcriptional activities and targets (Atlasi et al. 2008; Gabut et al. 2011). Similarly, isoforms of DNMT3B produced by AS are also known to be specific for stem cells, suggesting that AS regulation contributes to maintaining a stem cell-specific epigenetic state in ESCs (Gopalakrishna-Pillai and Iverson 2011; Liao et al. 2015).