“…Taguchi's approach assumed the decomposition of the experimental design into two distinct ones: the internal array, controlling highly controlled factors, and the external array, determining factors poorly controlled or simulated environmental disturbing factors. At the same time, mainly in the chemical industry, but also in metal industry (Lipiński, 2015;Lipiński and Wach, 2015), in anti-corrosion protection (Włodarczyk et al, 2011;Wrońska and Dudek, 2014;Lipiński, 2017), biotechnology (Skrzypczak-Pietraszek et al, 1993) and medical research (Wojnar et al, 2019), the response surface methodology (RSM) initiated by Box and Wilson (Box and Wilson, 1951), and later modified by Scheffe (Scheffe, 1958) for testing mixtures was developed. The main difference from the previously mentioned methods was the introduction of controlled factors with continuous settings and the imposition of the structure of the predictive model in the form of a predetermined function with unknown parameters.…”