Cortical blindness in a child with acute glomerulonephritis

Kaarthigeyan, K; Vijayalakshmi, A M

doi:10.4103/0971-4065.86408

Cited by 5 publications

(4 citation statements)

References 7 publications

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“…[ 1 ] Literature consists of few case reports or few small series of patients in different clinical settings. [ 1 2 3 4 5 6 7 ] All age groups are susceptible to the syndrome. The setting in which it was described included patients with hypertensive encephathalopathies, patients who were receiving immunosuppressive medicines after organ transplantation or other malignancies, patients with renal failure, and patients with eclampsia.…”

Section: Introductionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome in children with kidney disease

et al. 2014

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Posterior reversible encephalopathy syndrome (PRES) is a clinic-radiographic entity of heterogeneous etiologies that are grouped together because of similar findings on neuro-imaging and associated symptom complex of headache, vision loss, altered mentation, and seizures. Although usually considered benign and reversible, characteristics of this syndrome in pediatric patients remain obscure. This case series included 11 patients (8 males, 3 females, age 3-15 years) of PRES during September 2010 to February 2012 out of a total 660 renal pediatric patients (1.66%). We studied their clinical profile, contributory factors, and outcome. Presenting symptoms were headache in 73%, dimness of vision or cortical blindness in 36%, seizures in 91%, and altered mentation in 55%. The associated renal diseases were acute renal failure (55%), chronic renal failure (9%), and 36% had normal renal function. The contributory factors were uncontrolled hypertension (100%), severe hypoproteinemia (9%), persistent hypocalcemia (9%), hemolytic uremic syndrome (36%), cyclosporine toxicity (9%), lupus nephritis (9%), high hematocrit (9%), and pulse methylprednisolone (9%). Brain imaging showed involvement of occipito-parietal area (100%) and other brain areas (63%). All but one patient of hemolytic uremic syndrome had complete clinical neurological recovery in a week, and all had normal neurological imaging after 4-5 weeks. PRES is an underdiagnosed entity in pediatric renal disease patients. Associated hypertension, renal disease, and immunosuppressive treatment are important triggers. Early diagnosis and treatment of comorbid conditions is of prime importance for early reversal of syndrome.

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Section: Introductionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome in children with kidney disease

et al. 2014

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“…Gupta et al reported that PSGN with PRES presented with hypertension, transient vision loss with computed tomography of brain findings, which was reversed after hypertension control [13]. Kaarthigeyan and Vijayalakshmi reported a case with typical PSGN features and transient blindness [15].…”

Section: Discussionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome a rare presentation of post?streptococcal glomerulonephritis

Dudipala¹,

Prashanthi²,

Kumar³

2020

Indian J Child Health

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Acute post-streptococcal glomerulonephritis (PSGN) is a classic example of acute nephritic syndrome in children. It is typically characterized by gross hematuria, edema, hypertension, and acute kidney injury (AKI). Patients show diverse clinical profiles from being asymptomatic to mild syndrome or significant complications such as AKI, cardiac failure, or encephalopathy. Hypertension is found in up to 90% of patients and only 10% may have neurological symptoms. Only a few present with posterior reversible encephalopathy syndrome (PRES). Although PRES is a rare, but severe complication, there is a good outcome with appropriate treatment. Here, we report a case of PSGN in an 11-year-old female child who presented with altered sensorium, seizures, and vision loss. She was diagnosed as PRES on neuroimaging, which recovered with appropriate treatment.

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“…Subklinik APSGN çoğunlukla hastaların aile yakınları veya yakın temasta oldukları kimselerde tanımlanmaktadır (20,23) . (3,8,20,(24)(25)(26) .…”

Section: çOcuk Vakalardaki Daha Ender Apsgn Başvuru Kliniğiunclassified

Acute glomerulonephritis

Benzer¹,

Tülpar²

2016

Cocuk Dergisi

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Akut glomerülonefrit (AGN), glomerüllerdeki akut seyirli bir inflamasyonun oluşturduğu bir klinik sendromdur. Tipik başvuru bulguları, makroskopik hematüri, hipertansiyon ve ödem üçlüsünden oluşur. Çocuklarda AGN'nin en sık nedeni poststreptokoksik glomerülonefrittir. Geçirilmiş bir streptokok enfeksiyonu kanıtı olup olmadığı ve serum kompleman seviyesi AGN ayırıcı tanısında yol göstericidir. Tipik APSGN vakalarında böbrek biyopsisi endikasyonu yoktur. AGN etiyolojisine bakılmaksızın tüm hastalara öncelikle destek tedavisi uygulanır. Çocuklarda APSGN'nin kısa ve uzun dönem prognozu genellikle iyidir. Streptokok enfeksiyonlarına karşı etkin ve güvenli aşıların geliştirilmesi için çok sayıda klinik çalışma hâlen yürütülmektedir.

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Cortical blindness in a child with acute glomerulonephritis

Cited by 5 publications

References 7 publications

Posterior reversible encephalopathy syndrome in children with kidney disease

Posterior reversible encephalopathy syndrome in children with kidney disease

Posterior reversible encephalopathy syndrome a rare presentation of post?streptococcal glomerulonephritis

Acute glomerulonephritis

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