Cosmic metal enrichment is one of the key physical processes regulating galaxy formation and the evolution of the intergalactic medium (IGM). However, determining the metal content of the most distant galaxies has proven so far almost impossible; also, absorption line experiments at z > ∼ 6 become increasingly difficult because of instrumental limitations and the paucity of background quasars. With the advent of ALMA, far-infrared emission lines provide a novel tool to study early metal enrichment. Among these, the [C II] line at 157.74 µm is the most luminous line emitted by the interstellar medium of galaxies. It can also resonant scatter CMB photons inducing characteristic intensity fluctuations (∆I/I CMB ) near the peak of the CMB spectrum, thus allowing to probe the low-density IGM. We compute both [C II] galaxy emission and metalinduced CMB fluctuations at z ∼ 6 by using Adaptive Mesh Refinement cosmological hydrodynamical simulations and produce mock observations to be directly compared with ALMA BAND6 data (ν obs ∼ 272 GHz). The [C II] line flux is correlated with M UV as log(F peak /µJy) = −27.205 − 2.253 M UV − 0.038 M 2 UV . Such relation is in very good agreement with recent ALMA observations (e.g. Maiolino et al. 2015;Capak et al. 2015) of M UV < −20 galaxies. We predict that a M UV = −19 (M UV = −18) galaxy can be detected at 4σ in 40 (2000) hours, respectively. CMB resonant scattering can produce ±0.1 µJy/beam emission/absorptions features that are very challenging to be detected with current facilities. The best strategy to detect these signals consists in the stacking of deep ALMA observations pointing fields with known M UV −19 galaxies. This would allow to simultaneously detect both [C II] emission from galactic reionization sources and CMB fluctuations produced by z ∼ 6 metals. 1 In this work we assume a ΛCDM cosmology with total matter, vacuum and baryonic densities in units of the critical density Ω Λ = 0.727, Ω dm = 0.228, Ω b = 0.045, Hubble constant H 0 = 100 h km s −1 Mpc −1 with h = 0.704, spectral index n = 0.967, σ 8 = 0.811 (Larson et al. 2011).