Costs and benefits of interventions aimed at major infectious disease threats: lessons from the literature

Kellerborg, Klas; Brouwer, Werner; Baal, Pieter van

doi:10.1007/s10198-020-01218-4

Cited by 4 publications

(3 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, this is the first study to estimate the total direct costs of secondary care of COVID‐19 associated with overweight and obesity in Europe. The lack of knowledge on costs of COVID‐19 is in line with previous studies, which found that there is generally little evidence on the cost of infectious diseases 30,31 . Because COVID‐19 is a novel disease, the knowledge regarding the disease is limited and the long‐term effects are unknown.…”

Section: Discussionsupporting

confidence: 70%

Costs of the COVID‐19 pandemic associated with obesity in Europe: A health‐care cost model

et al. 2021

View full text Add to dashboard Cite

Summary Excess weight is associated with severe outcomes of coronavirus disease 2019 (COVID‐19). We aimed to estimate the total secondary care costs by body mass index (BMI, kg/m2) category when hospitalized due to COVID‐19 in Europe during the first wave of the pandemic from January to June 2020. Building a health‐care cost model, this study aimed to estimate the total costs of COVID‐19. Information on risk of hospitalization, admission to intensive care unit (ICU) and risk of ventilation were based on published data. Average cost per patient and in total were calculated based on risks of admission to ICU, risk of invasive mechanical ventilation and length of hospital stay when hospitalized and published costs associated with hospitalization. The total direct costs of secondary care during the first wave of COVID‐19 in Europe were estimated at EUR 13.9 billon, whereof 76% accounted for treating people with overweight and obesity. The average cost per hospital admission increased with BMI, from EUR 15831 for BMI <25 kg/m2 to EUR 30982 for BMI ≥40 kg/m2. This study reveals that excess weight contributes disproportionally to the costs of COVID‐19. This might reflect that overweight and obesity caused the COVID‐19 pandemic to result in more severe outcomes for citizens and higher secondary care costs throughout Europe.

show abstract

Section: Discussionsupporting

confidence: 70%

Costs of the COVID‐19 pandemic associated with obesity in Europe: A health‐care cost model

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Its design drew on the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement and a previous review of the costs and benefits of interventions aimed at major infectious disease threats. 13,14 We extracted data for all costed activities; outcomes of interest included the scope and type of costed preparedness activities, the costing methods, estimated costs, and cost drivers. LC and EP independently extracted data for studies and then cross-validated the data extraction.…”

Section: Data Collectionmentioning

confidence: 99%

The costs of improving health emergency preparedness: A systematic review and analysis of multi-country studies

et al. 2022

View full text Add to dashboard Cite

Background Investing in health emergency preparedness is critical to the safety, welfare and stability of communities and countries worldwide. Despite the global push to increase investments, questions remain around how much should be spent and what to focus on. We conducted a systematic review and analysis of studies that costed improvements to health emergency preparedness to help to answer these questions. MethodsWe searched for studies that estimated the costs of improving health emergency preparedness and that were published between 1 January 2000 and 14 May 2021, using PubMed, Web of Science, Google Scholar, EconLit, and National Health Service Economic Evaluation Databases (PROSPERO CRD42021254428). We also searched grey literature repositories and contacted subject experts. We included studies that estimated the costs of improving preparedness at the global level and/or at the national level across at least ten countries, covered two or more technical areas in the WHO Benchmarks for International Health Regulations (IHR) Capacities, and included activities focused on human health. We mapped costs across technical areas in the WHO Benchmarks for IHR Capacities.Findings Ten studies met our inclusion criteria. Costing methods varied substantially across included studies and cost estimates ranged from US$1¢6 billion per year to improve capacities across 139 low-and middle-income countries (LMICs) to US$43 billion per year to support national-level activities worldwide and implement global-level initiatives, such as research and development for health technologies (diagnostics, therapeutics, and vaccines). Two recent studies estimated costs by drawing on IHR Monitoring and Evaluation Framework country capacity data, with one study estimating costs across 67 LMICs of US$15¢4 billion per year (US$29¢1 billion including upfront capital costs) and the other calculating costs for the 196 States Parties to the IHR of US$24¢8 billion per year. Differences in included studies' methods, and the characteristics of countries considered, mean it is difficult to make like −for−like comparisons of the absolute costs or per-capita costs estimated by studies.Interpretation Improving health emergency preparedness worldwide will require substantial and sustained increases in investments. Further guidance on estimating the size of those investments can help to standardise methods, allowing greater interpretation and comparison across studies/countries. As well as greater transparency and detail in the reporting of methods by studies focused on this topic, this can help support estimates of global resource requirements and facilitate investments towards improving preparedness for future pandemics.

show abstract

“…A study in South Africa has suggested that a combination of interventions could be cost-effective (US$ 340 per lifetime years of lives saved). However, it is difficult to generalize the findings because of the different resources, threats, and living environments ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study

Wang

Shi

Huang

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

This study aimed to assess the cost-effectiveness of various public health measures in dealing with coronavirus disease 2019 (COVID-19) in China. A stochastic agent-based model was used to simulate the progress of the COVID-19 outbreak in scenario I (imported one case) and scenario II (imported four cases) with a series of public health measures. The main outcomes included the avoided infections and incremental cost-effectiveness ratios (ICERs). Sensitivity analyses were performed to assess uncertainty. The results indicated that isolation-and-quarantine averted the COVID-19 outbreak at the lowest ICERs. The joint strategy of personal protection and isolation-and-quarantine averted one more case than only isolation-and-quarantine with additional costs. The effectiveness of isolation-and-quarantine decreased with lowering quarantine probability and increasing delay time. The strategy that included community containment would be cost-effective when the number of imported cases was >65, or the delay time of the quarantine was more than 5 days, or the quarantine probability was below 25%, based on current assumptions. In conclusion, isolation-and-quarantine was the most cost-effective intervention. However, personal protection combined with isolation-and-quarantine was the optimal strategy for averting more cases. The community containment could be more cost-effective as the efficiency of isolation-and-quarantine drops and the imported cases increases.

show abstract

Costs and benefits of interventions aimed at major infectious disease threats: lessons from the literature

Cited by 4 publications

References 65 publications

Costs of the COVID‐19 pandemic associated with obesity in Europe: A health‐care cost model

Costs of the COVID‐19 pandemic associated with obesity in Europe: A health‐care cost model

The costs of improving health emergency preparedness: A systematic review and analysis of multi-country studies

Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study

Contact Info

Product

Resources

About