Cottonseed meal fermented by Candida tropical reduces the fat deposition in white-feather broilers through cecum bacteria-host metabolic cross-talk

Niu, Junli; Zhang, Jun; Wei, Lianqing; Ma, Xi; Zhang, Wenju; Nie, Cunxi

doi:10.1007/s00253-020-10538-7

Cited by 19 publications

(19 citation statements)

References 73 publications

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“…This result suggests a positive correlation between fat deposition and Lachnospiraceae abundance. A similar positive association of abdominal fat and subcutaneous fat thickness with Lachnospiraceae abundance was observed in broilers (43). Because it is a species of the family Lachnospiraceae, the abundance of Ruminococcus_torques_group is supposed to be positively related to fat accumulation.…”

Section: Discussionsupporting

confidence: 67%

Cecal Microbiota Modulates Fat Deposition in Muscovy Ducks

Lyu

Liu

et al. 2021

Front. Vet. Sci.

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Ducks with the same genetic background vary greatly in their adiposity phenotypes. The gut microbiota plays an essential role in host physiological development and metabolism including fat deposition. However, the association of the gut microbiota with the lipogenic phenotype of ducks remains unknown. In this study, we investigated the cecal microbiota of adult Muscovy ducks and the correlation of the cecal microbiota with fat phenotypes. A total of 200 Muscovy ducks were selected from a population of 5,000 Muscovy ducks to record their abdominal fat weight and collect their cecal contents after being slaughtered and defeathered. The cecal contents were subjective to DNA isolation and 16S rRNA gene sequencing. The results were sorted according to the percentage of abdominal fat and the top 20% (n = 40) and the bottom 20% (n = 40) were set as the high and low groups, respectively. Our results indicated that in the cecum of Muscovy ducks, Bacteroidetes, Firmicutes, and Fusobacteria were the predominant phyla while Bacteroides, Oscillospiraceae_uncultured, Parabacteroides, and Bacteroidales_norank were the top 4 dominant genera. Abdominal fat weight (18.57~138.10 g) and percentage of abdominal fat (1.02~27.12%) were significantly correlated (R2 = 0.92, P < 0.001). Although the lipogenic phenotypes of ducks had a significant difference (P < 0.05), the α-diversities of the high and low groups were not significantly different (P > 0.05). Nevertheless, after random forest analysis, we identified two genera, Treponema and Ruminococcus_torques_group, that were significantly associated with fat deposition in Muscovy ducks. In addition, the abundances of Treponema and Ruminococcus_torques_group gave a significantly negative and positive association with abdominal fat weight, respectively (P < 0.05). Ducks with a low level of Treponema exhibited a tendency toward a high percentage of abdominal fat (P < 0.01), while the percentage of abdominal fat in ducks with high Ruminococcus_torques_group abundance tended to be higher than that in ducks with low Ruminococcus_torques_group abundance (P < 0.01). These findings could provide the basic data on the cecal microbiota in Muscovy ducks as well as a theoretical foundation to limit the fat deposition by modulating the gut microbiota in the duck industry.

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Section: Discussionsupporting

confidence: 67%

Cecal Microbiota Modulates Fat Deposition in Muscovy Ducks

Lyu

Liu

et al. 2021

Front. Vet. Sci.

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“…Many studies suggest that food or feeds fermented by probiotics may be potentially an effective strategy to regulate the gut microbiota and its metabolites ( Azad et al, 2020 ; Niu et al, 2020 ; Gu et al, 2021 ; Li et al, 2021 ). The VFAs, especially butyric acid, as a microbial metabolite, can not only improve the growth performance, but also boost the immunity of piglets ( Fang et al, 2014 ; Zhao et al, 2018 ).…”

Section: Discussionmentioning

confidence: 99%

“…Fermented cottonseed meal (FCSM), a product produced by mixing solid CSM with liquid phases and then inoculating the mixture with beneficial microorganisms ( Sun et al, 2014 ), can reduce free gossypol and improve the protein quality of CSM with solid state fermentation ( Zhang et al, 2007 ). It has been suggested that the FCSM partial replacing SBM (about 6–8%) not only can improve the growth performance, immune and antioxidant capacity, and digestibility in broiler chickens ( Sun et al, 2013 ; Nie et al, 2015 ; Wang et al, 2017 ; Niu et al, 2020 ), but also can reduce the F:G (the ratio of feed and gain weight) and diarrhea rate in nursery pigs, growing pigs and finishing pigs ( Guan et al, 2017 ), which indicated that the FCSM has the potential to be a high-quality protein source.…”

Section: Introductionmentioning

confidence: 99%

Fermented Cottonseed Meal as a Partial Replacement for Soybean Meal Could Improve the Growth Performance, Immunity and Antioxidant Properties, and Nutrient Digestibility by Altering the Gut Microbiota Profile of Weaned Piglets

Wang

et al. 2021

Front. Microbiol.

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The study investigated the impact of fermented cottonseed meal (FCSM) on growth performance, immunity and antioxidant properties, nutrient digestibility, and gut microbiota of weaned piglets by replacing soybean meal with FCSM in the diet. The experimental piglets were fed with either the soybean meal diet (SBM group) or fermented cottonseed meal diet (FCSM group) for 14days after weaning. The digestibility of dry matter (DM), organic matter (OM), crude protein (CP), gross energy (GE), amino acids and nitrogen was higher in the FCSM diet than those in the SBM diet (p<0.05). The piglets in the FCSM group showed greater growth performance and lower diarrhea rate than those in the SBM group (p<0.05). The concentration of serum immunoglobulin G (IgG) and antioxidase, intestinal and hepatic antioxidase were increased and the concentration of malondialdehyde (MDA) in the serum was decreased in those piglets in the FCSM group compared to those piglets in the SBM group (p<0.05). The piglets in the FCSM group had a higher concentration of volatile fatty acids (VFAs) in their ileum and cecum and a higher Simpson index of ileum than piglets in the SBM group (p<0.05). The relative abundance of Lactobacillus and [Ruminococcus]_torques_group in ileum and Intestinibacter, norank_f_Muribaculaceae, unclassified_o_Lactobacillales and [Eubacterium]_coprostanoligenes_group in cecum were enhanced in piglets fed with the FCSM diet, whereas the relative abundance of Sarcina and Terrisporobacter were increased in piglets fed with the SBM diet. Overall, FCSM replacing SBM improved the growth performance, immunity and antioxidant properties, and nutrient digestibility; possibly via the alterant gut microbiota and its metabolism of weaned piglets.Graphical AbstractFermented cottonseed meal as a partial replacement for soybean meal could improve the growth performance, immunity and antioxidant properties, and nutrient digestibility by altering the gut microbiota profile of weaned piglets. SBM, soybean meal; FCSM, fermented cottonseed meal.

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“…Requires the sacrifice of chickens for sample collection, maintenance of cold chain after sample collection, and rapid processing of samples. ( Kers et al, 2019b ; Niu et al, 2020 ; Park et al, 2020 ; Slizewska et al, 2020 ) Others Fluorescein isothiocyanate–dextran (FITC-d) Blood Immunoassay Measures epithelial permeability Limited to research settings since the compounds need to be gavaged and monitored in blood as a tool to determine gut barrier failure ( Niewold, 2014 ; Immerseel, 2019 ; Barekatain et al, 2020 ; Vuong et al, 2021 ) …”

Section: Methods For Monitoring Shifts In Chicken Intestinal Statusmentioning

confidence: 99%

“…Monitoring the microbiota at flock-level using samples such as pooled excreta, litter or poultry dust would be perhaps an alternative to individual bird sampling as a way to reduce the noise generated by the within bird variation observed in GIT microbiota studies. Another approach for overcoming the variability of the GIT microbiota is to further interrogate the functionality of the observed microbial population, either by doing predictive functional bioinformatics analysis or by directly measuring microbial metabolites of interest in the cecum using high-performance liquid chromatography, which is particularly useful for measuring microbial fatty acids and lactic acid outputs that are related to gut health, or using liquid-chromatography-tandem mass spectroscopy, which captures the microbial metabolomic profile ( Kers et al, 2019b ; Niu et al, 2020 ; Park et al, 2020 ; Slizewska et al, 2020 ).…”

Section: Microbiota Profiles and Productive Performancementioning

confidence: 99%

Centennial Review: Factors affecting the chicken gastrointestinal microbial composition and their association with gut health and productive performance

Bindari

Gerber

2022

Poultry Science

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Maintenance of “gut health” is considered a priority in commercial chicken farms, although a precise definition of what constitutes gut health and how to evaluate it is still lacking. In research settings, monitoring of gut microbiota has gained great attention as shifts in microbial community composition have been associated with gut health and productive performance. However, microbial signatures associated with productivity remain elusive because of the high variability of the microbiota of individual birds resulting in multiple and sometimes contradictory profiles associated with poor or high performance. The high costs associated with the testing and the need for the terminal sampling of a large number of birds for the collection of gut contents also make this tool of limited use in commercial settings. This review highlights the existing literature on the chicken digestive system and associated microbiota; factors affecting the gut microbiota and emergence of the major chicken enteric diseases coccidiosis and necrotic enteritis; methods to evaluate gut health and their association with performance; main issues in investigating chicken microbial populations; and the relationship of microbial profiles and production outcomes. Emphasis is given to emerging noninvasive and easy-to-collect sampling methods that could be used to monitor gut health and microbiological changes in commercial flocks.

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Cottonseed meal fermented by Candida tropical reduces the fat deposition in white-feather broilers through cecum bacteria-host metabolic cross-talk

Cited by 19 publications

References 73 publications

Cecal Microbiota Modulates Fat Deposition in Muscovy Ducks

Cecal Microbiota Modulates Fat Deposition in Muscovy Ducks

Fermented Cottonseed Meal as a Partial Replacement for Soybean Meal Could Improve the Growth Performance, Immunity and Antioxidant Properties, and Nutrient Digestibility by Altering the Gut Microbiota Profile of Weaned Piglets

Centennial Review: Factors affecting the chicken gastrointestinal microbial composition and their association with gut health and productive performance

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