Abstract:PurposeThe catabolism of cholesterol in neurons leads to a more hydrophilic compound soluble form, the 24‐S‐hydroxycholesterol by means of an enzyme the CYP46A1.The aim of this study was to analyse the implication of 24‐S‐hydroxycholesterol (24‐S‐OHC) on Müller glial cells (MGC) membrane dynamics in the rat.MethodsMGC were grown in vitro from retinas of 10‐day‐old Long Evans rats. Cells were treated with 24‐S‐OHC (treatment) or ethanol (control) for 2 min or 6 h. From twenty millions of MGC in each group, lipi… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.