“…The role of H. pylori in the rosacea's pathogenesis remains controversial, which is mostly reported as an aggravating factor in rosacea and the target therapy is beneficial [ 51 ]. Other dysbacteriosis or targeted therapies have also attracted attention as they relate to skin microorganisms (S epidermidis [ 52 ]) and intestinal flora (E. coli Nissle therapy [ 53 ]). However, some studies have conducted superficial difference analyses.…”