Coupure sélective par l'hydrazine des groupements acétyles anomères de résidus glycosyles acétylés

Synthesis, Characterization, X-Ray Crystallography, and Antileishmanial Activities of N-Linked and O-Linked Glycopyranosides

“…The anomeric acetyl group was hydrolyzed selectively using hydrazinium acetate, in DMF [29][30][31]; the resulting hemiacetal was washed with water and brine and used without further purification. To the crude hemiacetal, monoester was added using EDC as a coupling agent.…”

Glycosyl Inositol Derivatives Related to Inositolphosphoglycan Mediators: Synthesis, Structure, and Biological Activity

“…[17] These glycosyl donors were prepared as indicated in Scheme 1. The acetylated donor 8 [18] was synthesized from the readily available derivative 6 [19] by selective removal of the 1-O-acetyl group [20] and trichloroacetimidate formation under established conditions. [16] The benzylated donor 12 [21] was prepared Abstract in Spanish: Se describe una estrategia sintØtica para la preparacio Ân de una serie de compuestos relacionados con los inositol fosfoglicanos propuestos como segundos mensajeros (compuestos 3-5) y sus correspondientes precursores (glicosil fosfatidilinositoles de tipo 1 y 2).…”

Stereoselective Total Synthesis of Wheat Flour Ceramide Dihexoside

“…The mixture was evaporated in vacuo and chromatography of the residue (Si02 , AcOEt-n-hexane =I : 4) gave compound 20 (889mg, 93%). (22). To a solution of compound 21 (402mg, 816,umol) and p-nitrobenzoyl chloride (182mg, 979 ,umol) in dichloromethane (!Om!)…”

“…brine, dried (MgS04 ), and evaporated in vacuo. Chromatography of the residue (Si02 , AcOEt-n-hexane= I: 4) gave compound 22 (25) and 3, (26). To a solution of compound 22 (1.3 g, 2.03 mml) in dichloromethane (40ml) was added satd.…”