“…24 However, the application of natural or chemically synthesized enzymes is limited due to their poor stability, challenges of large-scale production and weak targeting. 21 Recently, nanozymes, a class of nanomaterials possessing natural enzyme-like activity, have seen widespread application, namely, in environmental areas, 25,26 the food safety field 27 and in several biomedical modalities including antibacterial and wound-healing treatments as well as detection because of their typical characteristics, such as good stability, excellent enzyme activity, easy modification and improved targeting. 7,[28][29][30] Furthermore, since nanozymes respond to tumour-specific weakly acid microenvironments and • OH in situ, they can prevent side effects in normal tissues.…”