Cover Picture: Proteomic Atomics Reveals a Distinctive Uracil‐5‐Methyltransferase (Mol. Inf. 5/2020)

Abstract

The cover picture shows how proteome‐based atom (C, H, N, O, S) distributions across all species of the phylogenetic tree revealed U5MTase of Plasmodium falciparum as a distinguished possible therapeutic target which in turn was used for in silico structure‐based drug design strategies (i.e., 3D protein structure modeling, virtual chemical library screening, and molecular docking) to identify imanixil as potential inhibitory drug molecule that might serve as possible remedy for the treatment of malaria. More Details can be found in the Full Paper by Subrata Pramanik, Manisha Thaker, Ananda Gopu Perumal, Rajasekaran Ekambaram, Naresh Poondla, Markus Schmidt, Pok‐Son Kim, Arne Kutzner, and Klaus Heese, please see DOI: 10.1002/minf.201900135