COVID-19-Associated Case Fatality Rate in Subjects Under 18 Years Old in Mexico, up to December 31, 2020

Navarro-Olivos, Efraín; Padilla-Raygoza, Nicolás; Flores-Vargas, Gilberto; Gallardo-Luna, María de Jesús; Leon-Verdin, Ma Guadalupe; Lara-Lona, Elia; Vázquez, Francisco Javier Magos; Díaz-Martínez, Daniel Alberto

doi:10.3389/fped.2021.696425

Cited by 5 publications

(6 citation statements)

References 14 publications

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“…However, the setting in which the children were tested was, however, unclear. Such studies were classified as conducted in other settings [ 64 , 65 , 68 , 75 , 89 , 97 , 110 , 129 , 137 , 162 , 171 , 175 , 192 , 196 , 197 , 215 , 218 , 220 , 225 ].…”

Section: Resultsmentioning

confidence: 99%

Epidemiology and clinical features of SARS-CoV-2 infection in children and adolescents in the pre-Omicron era: A global systematic review and meta-analysis

Kulkarni,

Ismail,

Zhu

et al. 2024

J Glob Health

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Methods We searched MEDLINE, Embase, Global Health, CINAHL, China National Knowledge Infrastructure, Wanfang, CQvip, and the World Health Organization (WHO) COVID-19 global literature databases for primary studies recruiting children aged ≤18 years with a diagnosis of SARS-CoV-2 infection confirmed either by molecular or antigen tests. We used the Joanna Briggs Institute critical appraisal tools to appraise the study quality and conducted meta-analyses using the random effects model for all outcomes except for race/ethnicity as risk factors of SARS-CoV-2 infection. Results We included 237 studies, each reporting at least one of the study outcomes. Based on data from 117 studies, the pooled SARS-CoV-2 positivity rate was 9.30% (95% confidence interval (CI) = 7.15–11.73). Having a comorbidity was identified as a risk factor for SARS-CoV-2 infection (risk ratio (RR) = 1.33; 95% CI = 1.04–1.71) based on data from 49 studies. Most cases in this review presented with mild disease (n = 50; 52.47% (95% CI = 44.03–60.84)). However, 20.70% of paediatric SARS-CoV-2 infections were hospitalised (67 studies), 7.19% required oxygen support (57 studies), 4.26% required intensive care (93 studies), and 2.92% required assisted ventilation (63 studies). The case fatality ratio (n = 119) was 0.87% (95% CI = 0.54–1.28), which included in-hospital and out-of-hospital deaths. Conclusions Our data showed that children were at risk for SARS-CoV-2 infections and severe outcomes in the pre-Omicron era. These findings underscore the need for effective vaccination strategies for the paediatric population to protect against the acute and long-term sequelae of COVID-19. Registration PROSPERO: CRD42022327680.

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Section: Resultsmentioning

confidence: 99%

Epidemiology and clinical features of SARS-CoV-2 infection in children and adolescents in the pre-Omicron era: A global systematic review and meta-analysis

Kulkarni,

Ismail,

Zhu

et al. 2024

J Glob Health

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“…In Mexico, the CFR was 3.99% in children under 2 years and 0.45% in those between 12 and 17 years of age [33].…”

Section: Agementioning

confidence: 96%

“…In Mexico, until December 31, 2020, among 48,505 confirmed cases of COVID-19, males (50.43%) and females (49.57%), the CFR was 96% for males and 0.80% for females under 18 years of age [33].…”

Section: S Exmentioning

confidence: 99%

“…Navarro et al [33] reported that of 48,505 confirmed cases up to December 31, 2020, the CFR was the highest for children between 0 and 2 years of age (3.99), the highest among the Mexican child population. For pneumonia, the CFR was 15.46%, Epidemiology of SARS-CoV-2 Infection in Mexico and Latin America DOI: http://dx.doi.org/10.5772/intechopen.109802 but the OR was 63.90%, showing the strong effect of pneumonia on mortality in Mexican children.…”

Section: Fatality Of Casesmentioning

confidence: 99%

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Epidemiology of SARS-CoV-2 Infection in Mexico and Latin America

Padilla-Raygoza¹,

Flores-Vargas²,

Gallardo-Luna³

et al. 2023

Epidemiological and Clinico-Pathological Factors of COVID-19 in Children

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This chapter presents some insights into COVID-19 in children. We begin by summarizing the fundamental aspects of SARS-CoV-2 and COVID-19. We also cover issues about the severity of the disease and fatality and factors associated with the outcome of pediatric patients with COVID-19. Most evidence treated in this chapter comes from reports in Mexico, but a general landscape in Latin America is pictured. COVID-19 does not seem to be so severe among children. It is worth noting that those at higher risk are the children between 0 and 2 years who develop pneumonia. In this chapter, we did not discuss extensively the Multisystem Inflammatory Syndrome nor the social impact that the COVID-19 pandemic has had on children. Many studies used for this chapter relied on open data sources resulting from a surveillance system designed for the general population. Therefore, specific variables for children were not analyzed.

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“…However, immunosuppression and coinfection of pneumonia, below 5 years, were major factors of increase in Fatality Rate. 2 Studies have shown that children affected with COVID 19 are at a higher risk of vascular diseases like Kawasaki disease, Takayasu arteritis 3 and Acute Kidney Injury 4 . Multisystem Inflammatory Syndrome complication was also established to be higher among children affected by COVID-19.…”

Section: Introductionmentioning

confidence: 99%

Parents’ Perception Towards Covid-19 Vaccination for Children in Surat: A Cross Sectional Study

Mukherjee

Chaudhari

Patel

et al. 2022

Natl J Community Med

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Background: Vaccine hesitancy has been recognized as a public health issue which needs to be addressed urgently. With reopening of school unvaccinated children might become major carriers of COVID-19. An assessment of the determinants of vaccine hesitancy will aid in the acceleration of vaccine administration among children. Objective: This study aims to explore parental COVID-19 vaccine hesitancy in Surat and determine factors associated with it. Methodology: This is a cross sectional study in Surat among 250 participants selected from Rural and Urban field practice area by Systematic Random Sampling. Data collection was done by data collectors in an interview during the month of January and February, 2022. Univariate analysis was done, followed by Chi square test to establish associations. Predictors were determined by Binomial Logistic Regression. Results: Mean age of population was 31.3 + 10.7 years. Vaccine Hesitancy was recorded in 154 (61.6%) participants. Urban address (p=0.013), Full Vaccination status of parents (<0.001) and Perceived Benefits of vaccine to the child (p=0.001) were significant predictors of Vaccine Hesitancy. Conclusion: High proportion of Vaccine hesitancy was found in this study. Interventions can be planned on the basis of factors affecting Vaccine Hesitancy

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COVID-19-Associated Case Fatality Rate in Subjects Under 18 Years Old in Mexico, up to December 31, 2020

Cited by 5 publications

References 14 publications

Epidemiology and clinical features of SARS-CoV-2 infection in children and adolescents in the pre-Omicron era: A global systematic review and meta-analysis

Epidemiology and clinical features of SARS-CoV-2 infection in children and adolescents in the pre-Omicron era: A global systematic review and meta-analysis

Epidemiology of SARS-CoV-2 Infection in Mexico and Latin America

Parents’ Perception Towards Covid-19 Vaccination for Children in Surat: A Cross Sectional Study

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