COVID-19 presenting as intussusception in infants: A case report with literature review

Athamnah, Mohammad N.; Masade, Salim; Hamdallah, Hanady; Banikhaled, Nasser; Shatnawi, Wafa; Elmughrabi, Marwa; Azzam, Hussein S.O. Al

doi:10.1016/j.epsc.2021.101779

Cited by 17 publications

(34 citation statements)

References 25 publications

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“…Intussusception is known to be associated with viral infections, such as respiratory adenovirus [ 6 ] and rotavirus [ 7 ]. On the other hand, there have been reports of intussusception in an infant as a manifestation of COVID-19 [ 8 , 9 ], even though pediatric patients seem to have less incidence of COVID-19 overall; the mechanism by which this could occur in pediatric patients is not understood and could in fact be idiopathic [ 10 ]. With the current pandemic, widespread implementation of measures to prevent transmission of COVID-19, such as hand washing, gargling, mask wearing, and social distancing, has contributed to reducing the incidence of infectious viral diseases [ 4 , 5 ].…”

Section: Discussionmentioning

confidence: 99%

Decreased incidence of intussusception during the COVID-19 pandemic. Trends in pediatric surgical emergencies

et al. 2021

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Purpose Recent reports suggest that the COVID-19 pandemic may be influencing disease morbidity. The purpose of this study was to investigate pandemic-related changes in the incidence of pediatric surgical emergencies. Methods Data from patients with one of 8 typical conditions considered to be pediatric emergencies who presented at 3 hospitals close to central Tokyo were collated retrospectively from accident and emergency (AE) department records for 2020 and compared with data for 3 years prior to 2020. Results All subjects had similar demographic profiles. The total number of pediatric AE attendances from 2017 to 2020 was 2880 (2017: n = 600, 2018: n = 736, 2019: n = 817, and 2020: n = 727). Annual attendances were similar. Of the 8 conditions, there were significantly less cases of intussusception in 2020 than previously (23/727; 3.1% versus 132/2153; 6.1%) p < 0.01 and the number of emergency surgical interventions for intussusception was also significantly less in 2020 (0/23; 0% versus 13/132; 9.8%) p < 0.01. Conclusion The implementation of preventative measures to combat the COVID-19 pandemic in 2020 would appear to have influenced the etiopathogenesis of intussusception enough to significantly decrease its overall incidence and the requirement for emergency surgical intervention.

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Section: Discussionmentioning

confidence: 99%

Decreased incidence of intussusception during the COVID-19 pandemic. Trends in pediatric surgical emergencies

et al. 2021

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“…In particular, adenovirus, enterovirus, norovirus, rotavirus and human herpes virus 6 have been associated with intussusception in infants and young children (10). To the best of our knowledge, eight cases of intussusception being the presentation of COVID-19 in infants have been reported so far (11)(12)(13)(14)(15)(16)(17). The main findings from these reports are summarized in Supplementary Table 1.…”

Section: Discussionmentioning

confidence: 97%

“…Most reports describe an irritable baby with abdominal pain and jelly-like stools. Fever was documented in 5 cases ( 11 , 12 , 14 , 15 ). A concurrent or a recent history of respiratory tract infection was described in only three cases ( 11 – 13 ).…”

Section: Discussionmentioning

confidence: 99%

“…Surgical procedure was performed in four cases, two of which preceded by an unsuccessful pneumatic reduction ( 12 , 15 , 17 ). Only one case reported the patient's death due to the development of a multi-organ dysfunction syndrome ( 15 ), whereas the remaining cases were all discharged without sequelae ( 11 – 14 , 16 , 17 ).…”

Section: Discussionmentioning

confidence: 99%

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Intussusception in an Infant With SARS-CoV-2 Infection: A Case Report and a Review of the Literature

et al. 2021

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Coronavirus disease 2019 (COVID-19) is caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even if predominantly considered a respiratory pathogen, it could be associated with gastrointestinal involvement, generally in mild forms. Recent reports highlight the association between SARS-CoV-2 and intussusception in infants. A case of intussusception is hereby described in a previously healthy infant in whom the diagnosis of SARS-CoV-2 was made after the analysis of bronchoalveolar lavage and intraoperative specimens following surgical procedures. Accordingly, a review of infant cases with intussusception and SARS-CoV-2 infection is also reported.

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“…All children with acute abdomen should be evaluated for COVID 19. Out of all the atypical manifestations, intussusception being one of the rare manifestations of COVID 19 [1] .…”

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confidence: 99%

Intussusception as a Manifestation of COVID -19

Jayaram

Sareen

Dedwal

2021

Int J Health Sci Res

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COVID 19 has created a havoc in the world and has brought the world to a standstill. Everyday we get to learn something new about the powerful virus. COVID has different varied clinical presentations. Besides respiratory symptoms many children present with GI symptoms during this 2nd wave of COVID. We present a case of a 10 year male child who presented with features of intussusception with a history of URTI 5 days prior to acute abdomen. Unlike other cases where children respond nicely to post operative conventional treatment, this child went downhill inspite of aggressive management in PICU. In view of ongoing pandemic and mother who was found to be COVID positive, a thought if the child could be suffering from COVID and its complications. Throat swab for RTPCR SARS CoV-2 was found to be positive and acute viral inflammatory markers were found to be highly elevated. A diagnosis of Severe COVID-19 with cytokine storm manifesting as intussusception was made. All children with acute abdomen should be evaluated for COVID 19. Out of all the atypical manifestations, intussusception being one of the rare manifestations of COVID 19 [1]. Key words: Covid, intussusception, cytokine storm, RTPCR.

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COVID-19 presenting as intussusception in infants: A case report with literature review

Cited by 17 publications

References 25 publications

Decreased incidence of intussusception during the COVID-19 pandemic. Trends in pediatric surgical emergencies

Decreased incidence of intussusception during the COVID-19 pandemic. Trends in pediatric surgical emergencies

Intussusception in an Infant With SARS-CoV-2 Infection: A Case Report and a Review of the Literature

Intussusception as a Manifestation of COVID -19

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