COVID-19 Prophylaxis Efforts Based on Natural Antiviral Plant Extracts and Their Compounds

Abstract

During the time of the novel coronavirus disease 2019 (COVID-19) pandemic, it has been crucial to search for novel antiviral drugs from plants and well as other natural sources as alternatives for prophylaxis. This work reviews the antiviral potential of plant extracts, and the results of previous research for the treatment and prophylaxis of coronavirus disease and previous kinds of representative coronaviruses group. Detailed descriptions of medicinal herbs and crops based on their origin native area, plant parts used, and their antiviral potentials have been conducted. The possible role of plant-derived natural antiviral compounds for the development of plant-based drugs against coronavirus has been described. To identify useful scientific trends, VOSviewer visualization of presented scientific data analysis was used.

Covid-19 ile mücadelede bitkilerin rolü

“…Naja ve Hamdeh (2020), pandemi sürecinde bireysel, sosyal ve milli seviyelerde optimal beslenmeyi destekleyen çok seviyeli aksiyon planı belirlemişlerdir. Bu çalışmada asıl amaçlar, sağlıklı beslenmenin sürdürülmesi ve aynı zamanda kullanılabilen tüm bitkisel ürünler ile bitki türevleri hakkında kapsamlı bir bilimsel veri tabanının oluşturulmasına yöneliktir [6].…”

“…), zeytin yaprağı (Olea europea L.), meyan kökü (Glyrrhiza glabra L.) ve farklı kekik cinslerinin (Origanum, Thymus ve Thymbra) Covid-19 tedavisi için potansiyele sahip olarak görülmektedir [15]. Özellikle terpenoitler, alkaloitler, stilbenler ve flavonoitlerin bitkisel bazlı anti-viral ilaçların üretilmesi için temel biyolojik aktiviteye sahip metabolitler oldukları düşünülmektedir [6]. Şimdiye kadar; arktin, skutelarin, forsitozit, kaempferol, sekoksiloganin, nikotianamin, saikosaponin gibi çeşitli fitokimyasal bileşiklerin anti-SARS-CoV-2 aktivitesine sahip oldukları bildirilmiştir [8] (Tablo 3).…”

“…Bu süreç içerisinde de dünya genelinde hükümetler, sosyal teması azaltmak adına ülke çapında karantina uygulamalarına gitmiş, bir araya gelişler azaltılmaya çalışılmış ve maske takmak teşvik edilmiştir. Hijyen kuralları kapsamında alınan bu önlemler ile kısmi de olsa yayılma yavaşlatılmıştır [6].…”

Clitoria ternatea - Shifting Paradigms: From Laboratory to Industry

“…According to their findings, the highest antibacterial activity was observed for acetone and the lowest antibacterial activities were observed for isopropyl alcohol, and petroleum ether extracts against Proteus mirabilis. Interestingly, in a recent review in 2021 stated that Clitoria ternatea plant extracts contain antiviral potential and can be used for COVID-19 prophylaxis efforts based on natural antiviral Plant extracts and their compounds [23]. At the same time, it is worth mentioning here that in Srilankan traditional medicine treatment regime Clitoria ternatea has been mentioned as a suitable plant to treat rabies as well [9].…”

Untitled

“…Rios and Reco, 2005, observed that the interests of scientific community on healthcare applications of phytochemicals have been continuously increasing. [39,40] There is wide range of criteria that have been studied by the researchers. Many of them have focused on the antimicrobial properties of various extracts obtained from various parts of the plants based on traditional knowledge, folk medicines, essential oils, compounds isolated from plants, and various groups of phytochemicals such as flavonoids, terpenes, alkaloids, proteins, essential oils, and flavones.…”