COVID-19 Waterfall

Mohammadi, Shekoufeh; Varpaei, Hesam Aldin; Mohammadi, Mostafa

doi:10.5812/ans.118309

Cited by 2 publications

(3 citation statements)

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“…Among our relatively homogenous sample of COVID-19 patients admitted to the ICU, the prevalence of comorbidities was well matched with the reports of previous studies [ 2 ]. Hypertension, followed by diabetes, and cardiovascular diseases were the most commonly observed comorbidities among the participants of this study.…”

Section: Discussionsupporting

confidence: 80%

“…The clinical spectrum of coronavirus disease (COVID-19) varies from asymptomatic infection to severe pneumonia [ 1 ]. Because COVID-19 is an acute inflammatory phase (manifested as an unavoidable process in the form of fever, loss of appetite, and weight loss), patients must be able to withstand the inflammatory cascade resulting from those cytokine storms [ 2 ]. Given that the course of COVID-19 is likened to a waterfall, it seems that having a normal nutritional status can play a role in preventing the patient from falling into the abyss of the waterfall.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the Relationship between Nutritional Status of COVID-19 Patients Admitted to the ICU and Patients’ Prognosis: A Cohort Study

Mohammadi

Varpaei

Khamseh

et al. 2022

Journal of Nutrition and Metabolism

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Background. Malnutrition in COVID-19 critically ill patients can lead to poor prognosis. This study aimed to evaluate the association between nutritional status (or risk) and the prognosis of critically ill COVID-19 patients. In this study, prognosis is the primary outcome of “hospital mortality” patients. The second outcome is defined as “need for mechanical ventilation.” Methods and Materials. In this single-center prospective cohort study, 110 patients admitted to the Intensive Care Unit of Imam Khomeini Hospital Complex (Tehran, Iran) between April and September 2021 were enrolled. Participants formed a consecutive sample. MNA-SF, NRS-2002, mNUTRIC, and PNI scores were used to evaluate nutritional assessment. Patients’ lab results and pulse oximetric saturation SpO2/FiO2 (SF) ratio at the time of intensive care unit (ICU) admission were collected. Patients were screened for nutritional status and categorized into two groups, patients at nutritional risk and nonrisk. Results. Sixty-five (59.1%) of all patients were men. The overall range of age was 52 ± 15. Thirty-six (32.7%) of patients were obese (BMI ≥ 30). The hospital mortality rate was 59.1% (n = 65). According to the different criteria, malnutrition rate was 67.3% (n = 74) (NRS), 28.2% (n = 31) (MNA), 34.5% (n = 38) (mNUTRIC), and 58.2% (n = 64) (PNI). There was a statistically significant association between chronic kidney disease (CKD) and mNUTRIC risk (OR = 13.5, 95% CI (1.89–16.05), P = 0.002 ), diabetes mellitus (DM) and MNA risk (OR = 2.82, 95% CI (1.01–7.83), P = 0.041 ), hypertension (HTN) and MNA risk (OR = 5.63, 95% CI (2.26–14.05), P < 0.001 ), and malignancy and mNUTRIC risk ( P = 0.048 ). The nutritional risk (all tools) significantly increased the odds of in-hospital death and need for mechanical ventilation. The length of stay was not significantly different in malnourished patients. Conclusion. In the critical care setting of COVID-19 patients, malnutrition is prevalent. Malnutrition (nutritional risk) is associated with an increased risk of need for mechanical ventilation and in-hospital mortality. Patients with a history of HTN, CKD, DM, and cancer are more likely to be at nutritional risk at the time of ICU admission.

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Section: Discussionsupporting

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Evaluation of the Relationship between Nutritional Status of COVID-19 Patients Admitted to the ICU and Patients’ Prognosis: A Cohort Study

Mohammadi

Varpaei

Khamseh

et al. 2022

Journal of Nutrition and Metabolism

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“…[70][71][72][73][74] Due to the widespread applications of such heterocyclic scaffolds, numerous materials have been utilized for their synthesis. Such materials range from conventional Lewis acidic homogeneous to heterogeneous catalysts including zeolites, [75,76] mesoporous silica, [77] nanocomposites, [78] ionic liquids [79] and palladacycles supported over polymers. [80] While CPs have emerged as the excellent heterogeneous catalysts, MCRs require the presence of hydrogen bond donor (HBD) for multiple substrate anchoring followed by their coupling.…”

Section: Introductionmentioning

confidence: 99%

Cobalt Coordination Polymers Offering Hydrogen Bonding Cavities as Efficient Catalysts for Coupling Reactions

Pachisia,

Goyal,

Aashish

et al. 2023

ChemCatChem

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This work presents the synthesis and characterization of two cobalt‐based coordination polymers (CPs) prepared by using two positionally related pyridine‐2,6‐dicarboxamide fragment‐based ligands containing appended arylcarboxylic acid groups. While arylcarboxylate groups of ligands coordinate to the Co(II) ions to produce 2D CPs; the amidic N‐H groups remain free and generate large cavities lined with hydrogen bonds. Such hydrogen bonding cavities were found to reversibly adsorb molecular iodine. The Lewis acidic Co(II) ions and metal‐coordinated labile solvent molecules promoted noteworthy heterogeneous catalysis for Friedel crafts reactions as well as multicomponent condensation reactions.

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COVID-19 Waterfall

Cited by 2 publications

References 6 publications

Evaluation of the Relationship between Nutritional Status of COVID-19 Patients Admitted to the ICU and Patients’ Prognosis: A Cohort Study

Evaluation of the Relationship between Nutritional Status of COVID-19 Patients Admitted to the ICU and Patients’ Prognosis: A Cohort Study

Cobalt Coordination Polymers Offering Hydrogen Bonding Cavities as Efficient Catalysts for Coupling Reactions

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