2021
DOI: 10.1016/j.prp.2021.153384
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Covid19, beyond just the lungs: A review of multisystemic involvement by Covid19

Abstract: With the commencement of the COVID19 pandemic, following its 1 st case reported in Wuhan in China, the knowledge about the virus as well as the symptoms produced by the disease have drastically increased to this day. The manifestations of COVID19 have now known to affect multiple organ systems of the body, which have shown to have acute as well as chronic complications. Histopathological analysis of the biopsies from the affected organs have implied direct cytopathic effect of the virus … Show more

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Cited by 38 publications
(33 citation statements)
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“…Coronavirus disease 2019 (COVID‐19) is a pandemic disease which has caused a world health emergency 3 …”
Section: Year January 2015– December 2015 January 2016– December 2016 January 2017– December 2017 January 2018– December 2018 January 201mentioning
confidence: 99%
“…Coronavirus disease 2019 (COVID‐19) is a pandemic disease which has caused a world health emergency 3 …”
Section: Year January 2015– December 2015 January 2016– December 2016 January 2017– December 2017 January 2018– December 2018 January 201mentioning
confidence: 99%
“…These cytokines in turn recruit other white blood cells and generate an abrupt as well as cumulative surge of cytokines secretion namely the “cytokine storm”. Essentially, this uncontrolled and incessant hyper inflammation combined with the direct virus-induced damage features a multi-organ level clinical presentation including an acute respiratory distress syndrome (ARDS), thromboembolism, sepsis, acute cardiac injury, cardiovascular hypertension, nephric cellular damage, hematuria, hypoxemic injury to brain tissue and ultimately death [12] , [13] .…”
Section: Introductionmentioning
confidence: 99%
“…Coronavirus Disease 2019 (COVID- 19), the clinical disorder caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is characterised predominantly by pneumonitis with subsequent severe hypoxaemic respiratory failure [1]. In addition to the respiratory manifestations, multiple organ dysfunction such as acute kidney injury and myocarditis can occur [2]; only a few months into the pandemic, attention was drawn to the occurrence of neurological symptoms occurring in patients with COVID-19 [3]. Whilst many of these were simply symptoms commonly seen in febrile illnesses, such as headache and myalgia, a vast breadth of neurological disorders resulting from COVID-19 began to appear in the literature, including prolonged disorders of consciousness, immunologically mediated neurological diseases and cerebrovascular insults.…”
Section: Introductionmentioning
confidence: 99%