CPgeneProfiler: A lightweight R package to profile the Carbapenamase genes from genome assemblies

Abstract

"Carbapenems" are a specific subset of antibiotics considered to possess a higher spectrum of antimicrobial activity (Papp-Wallace, Endimiani, Taracila, & Bonomo, 2011) against Grampositive and Gram-negative bacteria. Even so, there are pathogens which are resistant to carbapenems due to the presence of carbapenemase genes (CP genes) which have the ability to hydrolyze carbapenems.