Craniofacial growth and dento-alveolar development in juvenile idiopathic arthritis patients

No association between types of unilateral mandibular condylar abnormalities and facial asymmetry in orthopedic-treated patients with juvenile idiopathic arthritis

“…9,15,[16][17][18] In a recent review, Peltomäki et al supported this perception and emphasized the need for documentation in future prospective longitudinal studies. 19 They further noted that altered dentofacial development may be caused by a combination of inflammatory effects on the intra-articular growth site of the condylar cartilage and impaired masticatory function. 19 There is currently a need to elucidate the intra-articular processes that occur during dysmorphic dentofacial development in JIA.…”

“…19 They further noted that altered dentofacial development may be caused by a combination of inflammatory effects on the intra-articular growth site of the condylar cartilage and impaired masticatory function. 19 There is currently a need to elucidate the intra-articular processes that occur during dysmorphic dentofacial development in JIA. This is important from a pathogenic perspective to advance our diagnostic and therapeutic understanding of this challenging condition.…”

Jaw surgery for correction of dentofacial anomalies caused by JIA

“…Furthermore, mandibular asymmetry is a frequent 4 finding (9). As a consequence of the skeletal changes, the development of the soft tissue and muscles is compromised resulting in a reduced length and volume (7).…”

“…However, the maxilla, the dentoalveolar development and the soft tissue are also influenced by the TMJ arthritis (7).…”

Silent Joint in Dispute. Is Intraarticular Treatment of Temporomandibular Joint Questionable?

“…Mandibular development is strongly dependent on the lengthening of the condyle provided by bone formation, which is in turn dependent on endochondral ossification of the secondary cartilage forming part of the condylar growth zone directly facing the inferior joint space. Different cartilage exists for articulation and growth in synovial joints while the TMJ presents the growth site in relation to the articulating cartilage, implicating a direct influence of inflammation in the growth process 15 and a possible adverse effect for local medical agents such as corticosteroids.…”