Creating Embryos for Research

Gerrand, Nicole

doi:10.1111/j.1468-5930.1993.tb00074.x

Cited by 12 publications

(3 citation statements)

References 8 publications

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“…Raymond added "Creating embryos for research is being examined out of concern for the independence and the interests of the women donating oocytes for research" [17]. After all, women must undergo invasive processes, which has some health risks.…”

Section: Some Views and Discussion On Embryo Researchmentioning

confidence: 99%

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Perspective Chapter: What about Embryo’s Rights?

Uslu¹

2023

Embryology Update

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The scientific associations of human reproduction experienced fundamental change in the twentieth century, with the development of in vitro fertilization for the treatment of infertility. The separation of sex and hi-tech reproduction treatments led to a revolution of gender and similarity relations, while embryo diagnostics led to a shift from scheduling families to planning a child. Furthermore, the presence of fertilized eggs outside the womb is a new form of human life which can be conserved and manipulated and the embryo in the petri dish in laboratory has become the entity of reproductive market, driven by clients and their claim to a right to reproductive choice. These improvements encounter deep-set moral sensitivities of human self-respect and the relation of human beings to their own nature. The conclusion is that the prospect of a posthuman future sounds for an ethic of care and responsibility. This chapter firstly presents these moral approaches briefly, especially regarding interventions in preimplantation-stage embryos in the laboratory, suggesting environmentally suitable laboratory conditions for this entity. Additionally, new suggestions for legitimately suitable regulations takes care precisely embryo’s right, but also embryology laboratory personnel, clinics and parents.

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Section: Some Views and Discussion On Embryo Researchmentioning

confidence: 99%

“…After all, women must undergo invasive processes, which has some health risks. Additionally, there is a risk of abuse, in view of the temptation to withhold detailed information on risks for anxiety of losing 'willing' candidate donors [17,18].…”

Section: Some Views and Discussion On Embryo Researchmentioning

confidence: 99%

Perspective Chapter: What about Embryo’s Rights?

Uslu¹

2023

Embryology Update

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“…One of the ethical problems posed by GGE research is related to the use and destruction of embryos, which may be viewed as an even greater concern when embryos are created specifically for research (e.g., in the study by Ma et al 9 ). 10 The creation of embryos specifically for the purposes of research may have some advantages over using supernumerary embryos ''left over'' after in vitro fertilization procedures. Namely, GGE can be conducted at an earlier stage of development of an embryo, or even at the moment of fertilization, in order to avoid mosaicism.…”

Section: Introductionmentioning

confidence: 99%

Germline Genome Editing Research: What Are Gamete Donors (Not) Informed About in Consent Forms?

Niemiec

Howard

2020

The CRISPR Journal

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The potential for using germline genome editing (GGE) in humans has garnered a lot of attention, both for its scientific possibilities as well as for the ethical, legal, and social challenges it ignites. The ethical debate has focused primarily on the suggestions of using GGE to establish a pregnancy (i.e., to offer it in a clinical setting), which is, to date, illegal in many jurisdictions. The use of GGE in research (where a pregnancy would not be established) has received much less attention, despite the fact that it raises serious ethical and social issues as well. Herein, we report on the analysis of informed consent forms for egg and sperm donation used in a widely publicized study where genome editing was used to correct a disease-causing genetic mutation in human embryos. Importantly, embryos were created using eggs and sperm obtained specifically for these experiments. The analysis indicates deficiencies in how the forms addressed various issues, including limited and potentially misleading information about the sensitive nature of the study, the lack of an explicit mention of genomic sequencing, as well as the poor readability of the forms. Furthermore, the arguably high compensation of U.S.$5,000 for egg donors raises questions about undue inducement to participate in research. Moreover, since the procurement of eggs involves serious health risks, it may be questioned whether research requiring such a procedure should be pursued. If such experiments are continued, donors should be informed about all relevant aspects in order to make informed decisions about participating.

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Using and Misusing Embryos: The Ethical Debates

Almond

2009

Philosophy and Medicine

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Creating Embryos for Research

Cited by 12 publications

References 8 publications

Perspective Chapter: What about Embryo’s Rights?

Perspective Chapter: What about Embryo’s Rights?

Germline Genome Editing Research: What Are Gamete Donors (Not) Informed About in Consent Forms?

Using and Misusing Embryos: The Ethical Debates

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