Creatinine Clearance in Critically Ill Surgical Patients

ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery

“…4 Creatinine clearance, another indicator of renal function, has been used to predict postoperative complications. 29,30 Creatinine clearance incorporates serum creatinine, age, and weight to provide a more accurate assessment of renal function than serum creatinine alone. Kertai and colleagues evaluated 852 subjects undergoing major vascular surgery and demonstrated an increase in mortality as both serum creatinine increased and creatinine clearance decreased, with creatinine clearance providing a more accurate assessment.…”

2009 ACCF/AHA Focused Update on Perioperative Beta Blockade Incorporated Into the ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery

“…One large study has shown that a preoperative creatinine level greater than 2 mg per dL is a significant, independent risk factor for cardiac complications after major noncardiac surgery (4). Creatinine clearance, another indicator of renal function, has been used to predict postoperative complications (29,30). Creatinine clearance incorporates serum creatinine, age, and weight to provide a more accurate assessment of renal function than serum creatinine alone.…”

ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery

“…Creatinine clearance, another indicator of renal function, has been used to predict postoperative complications (29,30). Creatinine clearance incorporates serum creatinine, age, and weight to provide a more accurate assessment of renal function than serum creatinine alone.…”