Critical temperature threshold measurement for cold urticaria: a randomized controlled trial of H
            <sub>1</sub>
            ‐antihistamine dose escalation

Magerl, Markus; Pisarevskaja, Dina; Staubach, Petra; Martus, Peter; Church, Martin K.; Maurer, Marcus

doi:10.1111/j.1365-2133.2012.10822.x

Cited by 54 publications

(56 citation statements)

References 8 publications

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“…Two previous studies have shown a decrease in the CTT after a therapeutic intervention in ACU (19,34). Mlynek et al (19) showed a correlation between decrease in CTT and clinical improvement of the disease.…”

Section: Discussionmentioning

confidence: 97%

“…Furthermore, none of these non-standardized and subjective methods of assessing clinical response to treatment appear to be reproducible. Siebenhaar et al (17) describe the objective measurement of disease activity and the response to therapeutic interventions using electronic TempTest ® equipment (34). This reli able method enables the precise and accurate control of treatment effects on the basis of monitoring threshold temperatures.…”

mentioning

confidence: 99%

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Temperature Thresholds in Assessment of the Clinical Course of Acquired Cold Contact Urticaria: A Prospective Observational One-year Study

Martínez-Escala

Curto‐Barredo²,

Carnero³

et al. 2015

Acta Derm Venerol

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Cold contact urticaria is the second most common subtype of physical urticaria. Cold stimulation standardized tests are mandatory to confirm the diagnosis. The aim of this study is to define the utility of determining thresholds (critical time and temperature) in assessment of the clinical course of typical acquired cold contact urticaria. Nineteen adult patients (10 women and 9 men; mean age 45 years) were included in the study and the diagnosis was confirmed with the ice-cube test and TempTest 3.0. Patients were treated continuously for 1 year with 20 mg/day rupatadine (anti-H1). Thresholds measurements were made before and after treatment. Improvements in temperature and critical time thresholds were found in the study sample, demonstrating the efficacy of continuous treatment with rupatadine. In most cases association with a clinical improvement was found. We propose an algorithm for the management of acquired cold contact urticaria based on these results.

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Section: Discussionmentioning

confidence: 97%

mentioning

confidence: 99%

Temperature Thresholds in Assessment of the Clinical Course of Acquired Cold Contact Urticaria: A Prospective Observational One-year Study

Martínez-Escala

Curto‐Barredo²,

Carnero³

et al. 2015

Acta Derm Venerol

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“…2,4,5,13 However, reduction of urticarial symptoms in many patients requires antihistamines at high doses, up to 4 times the standard dose. 4,5,[13][14][15] In our series, 85% of the patients who were treated with antihistamines showed significant clinical improvement. Rates of satisfactory clinical response with antihistamines ranged from 60% to 70% in previous series.…”

Section: Discussionmentioning

confidence: 98%

Acquired cold urticaria: Clinical features, particular phenotypes, and disease course in a tertiary care center cohort

Deza

Brasileiro

Bertolín‐Colilla

et al. 2016

Journal of the American Academy of Dermatology

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“…An example is chronic urticaria, a "non-anaphylactic" allergic disease, with enormous life-threatening potential. 57 In humans, an observation period of 6-8 h for patients with respiratory symptoms and 12-24 h for patients with hypotension and collapse is recommended due to possible biphasic reactions, but should be assessed on a case-by-case basis. 11,12 An anaphylaxis veterinary review recommended 3 days, but this was not based on clinical data from studies.…”

Section: Discussionmentioning

confidence: 99%

Triggers, risk factors and clinico‐pathological features of urticaria in dogs – a prospective observational study of 24 cases

Rostaher¹,

Hofer‐Inteeworn

Kümmerle‐Fraune

et al. 2017

Advances in Veterinary Dermatology

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Background -Urticaria and anaphylaxis are frequently encountered in veterinary practice, but little is known about the causes and relative frequencies of these reactions.Hypothesis/Objectives -This study was designed to improve current knowledge on the triggers, risk factors and clinico-pathological features of urticaria.Animals -Twenty four dogs with signs of urticaria with or without anaphylaxis.Methods -The study included dogs with cutaneous immediate-type hypersensitivity reactions. The cases were grouped by clinical severity into either an urticaria or an anaphylaxis group. All treatments and diagnostic tests (haematology, biochemical profile, allergy investigation) were recorded. A causality algorithm for urticaria and anaphylaxis (ALUA) was designed to determine the probability of the identified triggers and cofactors. Disease incidence, breed, age and gender predispositions were evaluated statistically.Results -Sixteen of 24 urticaria cases were associated with anaphylaxis whilst 8 of 24 were confined to the skin. The annual hospital incidence was 0.12%. Females seemed to be over-represented (2.4:1) and most of the dog breeds were pure breed (22 of 24), with Rhodesian ridgeback, boxer, beagle, Jack Russell terrier, French bulldog and Vizslas over-represented. In addition to skin lesions, the most frequently and severely affected organ systems were the gastrointestinal and cardiovascular systems. The predominant blood abnormalities were elevated lipase and alanine aminotransferase values. Insects, food and drugs were the most commonly identified triggers.Conclusions -To the best of our knowledge, this is the first study describing the trigger factors and clinicopathological features of dogs with urticaria in veterinary medicine. Insects, food and drugs were the most frequently detected triggers.

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Critical temperature threshold measurement for cold urticaria: a randomized controlled trial of H ₁ ‐antihistamine dose escalation

Abstract: Measurement of CTT allows for individualized risk management and therapy in patients with cold urticaria.

Cited by 54 publications

References 8 publications

Temperature Thresholds in Assessment of the Clinical Course of Acquired Cold Contact Urticaria: A Prospective Observational One-year Study

Temperature Thresholds in Assessment of the Clinical Course of Acquired Cold Contact Urticaria: A Prospective Observational One-year Study

Acquired cold urticaria: Clinical features, particular phenotypes, and disease course in a tertiary care center cohort

Triggers, risk factors and clinico‐pathological features of urticaria in dogs – a prospective observational study of 24 cases

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Critical temperature threshold measurement for cold urticaria: a randomized controlled trial of H 1 ‐antihistamine dose escalation

Abstract: Measurement of CTT allows for individualized risk management and therapy in patients with cold urticaria.

Cited by 54 publications

References 8 publications

Temperature Thresholds in Assessment of the Clinical Course of Acquired Cold Contact Urticaria: A Prospective Observational One-year Study

Temperature Thresholds in Assessment of the Clinical Course of Acquired Cold Contact Urticaria: A Prospective Observational One-year Study

Acquired cold urticaria: Clinical features, particular phenotypes, and disease course in a tertiary care center cohort

Triggers, risk factors and clinico‐pathological features of urticaria in dogs – a prospective observational study of 24 cases

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Critical temperature threshold measurement for cold urticaria: a randomized controlled trial of H ₁ ‐antihistamine dose escalation