Crossbreeding Effects and Polymorphic Associations of Genotypes of Gh Gene With Growth Traits in Rabbits

Zaghloul, Abd El Fatah; Khalil, M. H.; Eraky, Mahmoud; Nagaar, Ayman El; Ramadan, Shereif

doi:10.21608/ejrs.2019.81100

Cited by 8 publications

(12 citation statements)

References 17 publications

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“…These are of high heritability and higher than those found by Zaghloul et al (2019) and Khalil and Al-Homidan (2014) who report heterosis of 18 to 34% in weight gain and 19 to 20% at final weight. Regard feed consumption and CONV, the heterosis found was 22.58% and 23.44%, respectively, which are of moderate tendency.…”

Section: Fattening Phasementioning

confidence: 51%

Productive performance and carcass characteristics of New Zealand white and California rabbits and their crosses

Macias-Fonseca

Haro

Martínez

et al. 2021

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Objective: Evaluate the growth performance and carcass characteristics as well as the individual and maternal heterosis effects of New Zealand White (NZB), California (CA) rabbits and their crosses.Design/methodology/approach: 450 offspring rabbits, from 48 females mated to 6 stud rabbits, were evaluated, recording the weight (PNC) and litter size at birth (TCN) and at weaning (TCD), as well as, and weight (PMS), weight gain (GMD), consumption (CMS), and feed conversion (CONV) for during 8 weeks post-weaning. The carcass live weight at slaughter, warm carcass weight with head, carcass yield, and carcass parts of the carcass were evaluated.Results: Showed differences (p <0.05) in TCN and TCD with values of 10.47 and 9.03 kits, respectively. When NZB was used as the paternal breed, obtaining an individual heterosis of 5.91% for litter size and 12.44% for weaning weight. In the productive performance and carcass characteristics, the superiority of the California breed as a paternal breed was evidenced, with average values of 36.05 g in GMD and 2.95 kg in CONV. The averageindividual weight at the end of the fattening, at 70 days of age, was 2.09 kg and the weight of the carcass 1.16 kg. Post-weaning heterosis for the characteristics evaluated during fattening was were positive and moderate.Limitations on study/implications: It is necessary to carry out genetic improvement studies, with different crossing systems and to evaluate results based on the productive and reproductive behavior.Findings/conclusions: in reproductive characteristics, when using NZB as apaternal breed, the offspring are superior to those obtained from CA; while inthe productive variables, the offspring from CA show superior results.

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Section: Fattening Phasementioning

confidence: 51%

Productive performance and carcass characteristics of New Zealand white and California rabbits and their crosses

Macias-Fonseca

Haro

Martínez

et al. 2021

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“…It was also associated with birth weight and body weight at 35 days of age in BGG rabbits [20]. In Egypt, the association of the same SNP with body weights at 28, 42, and 56 days of age in the APRI and Moshtohor rabbits was reported [19], and with body weights at 28, 56, 70, and 84 days of age in Moshtohor and V-line rabbits [18]. El-Sabrout and Aggag [52] also genotyped the GH gene in V-line and Alexandria-line rabbits, but they did not detect any mutations.…”

Section: Plos Onementioning

confidence: 88%

“…The GH in rabbits has a vital role in postnatal growth and is involved in the regulation of different biological and metabolic functions, including muscle mass accretion, and bone growth [16][17][18]. The polymorphisms in the GH gene have shown significant associations with body weight in rabbits [15,19]. However, there is only one study that addressed the association of GH polymorphisms with carcass or meat quality traits in rabbits [20].…”

Section: Introductionmentioning

confidence: 99%

Influence of polymorphisms in candidate genes on carcass and meat quality traits in rabbits

Safaa,

Ragab,

Ahmed

et al. 2023

PLoS ONE

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Candidate gene is a powerful approach to study gene-trait association and offers valuable information for genetic improvement using marker-assisted selection. The current work aimed to study the polymorphisms of four single nucleotide polymorphism (SNPs) at located growth hormone (GH), insulin-like growth factor-II (IGF-II), fat mass and obesity-associated (FTO), and insulin receptor substrate-1 (IRS-1) genes, and their association with the carcass, and meat quality traits in rabbits. The SNPs were genotyped using RFLP-PCR in New Zealand White and local Baladi rabbits. The results revealed that the heterozygous genotype was the most frequent in all cases, except for the FTO SNP in LB rabbits. There was a significant effect for GH genotypes on meat lightness after slaughter and hind-part weight. While, IGF-II mutation significantly affected slaughter, hot carcass, commercial carcass, and hind-part weights. The FTO SNP was associated with cooking loss and intramuscular fat weight, and the IRS-1 SNP was significantly associated with drip loss and intramuscular fat. Specific-breed effects were obtained for IGF-II SNP on cooking loss, and for the intramuscular fat. Although the results suggested that these mutations are useful candidate genes for selection, more research for detecting more variants associated with carcass and meat quality traits in rabbits are recommended.

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“…A tubular-shaped, pelletized (4 mm diameter, 9 mm length) commercial ration was utilized. The ration formulated according to Zaghloul et al (2019), contained 24% soybean meal, 23% barley, 21% berseem hay, 19% wheat bran, 18.01% crude protein 13% yellow corn, 11.5% crude fiber, 2.5% fat, 1% limestone, 0.5% table salt, 14 kg di-calcium phosphate/ton, 1 kg anti-toxicity/ton, 1 kg anti-coccidial/ton, and 1 kg of a mineral mixture/ton, as per the National Research Council (NRC,1977).…”

Section: Methodsmentioning

confidence: 99%

MC4R gene polymorphisms for classification of growth efficiency and carcass measurements in two rabbit breeds in Egypt

Radwan¹,

Ateya²,

Elfad³

et al. 2023

SA J. An. Sci.

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Melanocortin 4 receptor (MC4R), a protein derived from the MC4R gene, is involved in feed intake, metabolism control, and body weight regulation in humans. The purpose of this research was to explore MC4R polymorphisms alongside metabolic marker changes and their relationship with growth and carcass measurements in rabbits. Using synthetic line V (V-line) and Baladi Black rabbit breeds (60 rabbits per breed), blood samples were collected for DNA extraction and biochemical analysis. The polymerase chain reaction (PCR) product of MC4R (493 bp) revealed five nonsynonymous single nucleotide polymorphisms (SNPs; submitted to GenBank with accession numbers gb|MT832144|, gb|MT832145|, and gb|MT832146|). Four SNPs were characteristic of the V-line breed, and one was characteristic of the Baladi Black. For classification of the defined SNP-dependent groups within and between breeds, a discriminant analysis model correctly classified a percentage of cases with the following predictor variables: 90.8% for body weight at 5–14 weeks of age; 85% for feed consumption, daily feed intake, and feed conversion ratio; and 93.3% for carcass measurements (for which hind part weight, liver weight, and liver percentage were the best predictors in both breeds). There were significant differences between and within V-line and Baladi Black breeds in agreement with metabolic biochemical marker profiles and the defined SNPs. The identified SNPs in the MC4R gene and profile of the investigated metabolic biomarkers could be used as candidates and reference for the effective characterization of the two rabbit breeds. This study could therefore facilitate the introduction of markerassisted selection for growth performance characteristics in rabbits.

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Crossbreeding Effects and Polymorphic Associations of Genotypes of Gh Gene With Growth Traits in Rabbits

Cited by 8 publications

References 17 publications

Productive performance and carcass characteristics of New Zealand white and California rabbits and their crosses

Productive performance and carcass characteristics of New Zealand white and California rabbits and their crosses

Influence of polymorphisms in candidate genes on carcass and meat quality traits in rabbits

MC4R gene polymorphisms for classification of growth efficiency and carcass measurements in two rabbit breeds in Egypt

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