Abstract.With reducing feature size of transistors and increasing of cores on a single chip, to overcome poor scalability and bandwidth limitation on a single bus, Network-on-Chip (NoC) has been proposed. However, reliability of Multiprocessor system based on Network-on-Chip (NoC) has become a significant challenge due to the transmission fault. The paper analyzes some fault-tolerant Routing methods based on retransmission, and hybrid error detection and retransmission fault-tolerant scheme is presented. Instead of using a simplex end-to-end (e2e) or router-to-router (r2r) error detection, the paper utilizes both of these two mechanisms which means head flit uses r2r while data flit uses e2e retransmission. To make the cost lower, in r2r error detection and retransmission operation, the paper employs comparator instead of encoder/decoder. At last, the advantages and disadvantages of different retransmission fault-tolerant routing mechanism are analyzed and the trend of this field is proposed.