Crown‐rump length audit plots with the use of operator‐specific PAPP‐A and <i>β</i>‐hCG median MoM

Sabrià, J.; Guirado, L.; Miró, Isabel; Gómez‐Roig, M.; Borrell, Antoni

doi:10.1002/pd.4996

Cited by 5 publications

(8 citation statements)

References 24 publications

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“…indicated a systematic CRL bias among 36% of the sonographers, and 60% of those had a CRL bias of more than 2 mm 21 .…”

Section: Discussionmentioning

confidence: 95%

“…Numerous studies have quantified measurement error variability in CRL in terms of limits of agreement, SDs of differences between operators, variance components and interclass correlation coefficients 13,14,21 . Results have been presented for intraobserver variation between measurements taken by the same sonographer and for interobserver variation between measurements taken by different sonographers.…”

Section: Distribution Of Crown-rump Length Measurement Errorsmentioning

confidence: 99%

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Crown–rump length measurement error: impact on assessment of growth

Gadsbøll

Wright

Kristensen

et al. 2021

Ultrasound in Obstet & Gyne

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What are the novel findings of this work?Even small errors in the first-trimester measurement of crown-rump length (CRL) significantly affect secondand third-trimester estimated fetal weight (EFW). A measurement error of −2 mm in first-trimester CRL shifts an EFW on the 10 th percentile at the 20-week scan to around the 20 th percentile. A measurement error of + 2 mm shifts an EFW on the 10 th percentile to around the 5 th percentile. What are the clinical implications of this work?Published data suggest that CRL measurement errors of 2 mm or more are common in clinical practice. Misclassification as small-, appropriate-or large-for-gestational age will commonly occur and affect clinical assessment, patient management and research results. Thus, there is a need to increase awareness of the importance of correct CRL measurement and to reduce measurement error variation through standardization and quality control.

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“…indicated a systematic CRL bias among 36% of the sonographers, and 60% of those had a CRL bias of more than 2 mm 21 .…”

Section: Discussionmentioning

confidence: 95%

Section: Distribution Of Crown-rump Length Measurement Errorsmentioning

confidence: 99%

Crown–rump length measurement error: impact on assessment of growth

Gadsbøll

Wright

Kristensen

et al. 2021

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

show abstract

“…Mathematical models [40,41] are implemented, and surveillance and prevention models will be offered. As will be further described in the methodology -the larger the risk, the earlier will be the GA at delivery, adding to the increase burden of prematurity [42][43][44][45][46][47][48][49][50].…”

Section: Methodsmentioning

confidence: 99%

Pre-Twin Screen - A Multi-Disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies

Meiri¹,

Kugler²,

Svirsky³

et al. 2020

Int J Women's Health Wellness

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The prevalence of twin pregnancies is rising globally due to increased assisted conception and advanced maternal age in pregnancy. Twin pregnancies have 5-9 times higher frequencies of fetal chromosomal and structural abnormalities, often deliver preterm, and have high prevalence of gestational diabetes mellitus (GDM), preeclampsia (PE), and intrauterine growth restriction (IUGR) compared to singletons. Twins have special complications such as twins-to twin transfusion syndrome in mono chorionic (MC) twins. Consequently, more twins are born prematurely, suffer from low birth weight, cerebral palsy, etc., often requiring admission to newborn intensive care units, and develop motor and cognitive disorders for life. These impose a huge burden on individuals, families, and the society.

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“…Large-scale quantitative evaluation of CRL measurement quality based on the distribution of data is less challenging, with the drawback that reference biometric data are not available for comparative analyses, as it is the case of NT. Some authors have proposed to use specific deviations of biochemical markers (PAPP-A and βhCG), which are the result of systematic CRL measurement bias [20].…”

Section: Crl Measurement Quality Control Methodsmentioning

confidence: 99%

Prenatal screening and diagnosis of genetic abnormalities: SEGO, SEQC^ML, AEDP consensus recommendations

Prieto

Adiego

Suela³

et al. 2020

Advances in Laboratory Medicine / Avances en Medicina De Laboratorio

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In this paper, the scientific societies SEGO, SEQCML and AEDP provide a series of consensus-based recommendations for prenatal screening and diagnosis of genetic abnormalities. A set of evaluation indicators are also proposed as a means to improve the quality of the biochemical, ultrasound, and genetic processes involved in prenatal screening and diagnosis of genetic anomalies. Some recommendations are also proposed in relation to invasive prenatal diagnostic procedures, more specifically regarding sample collection and genetic testing. The purpose of this proposal is to unify performance criteria and quality indicators at national level, with audits performed on a regular basis. It is strongly recommended that a national prenatal screening strategy be established and provided with the resources necessary to evaluate the performance of quality indicators and diagnostic procedures under the supervision of health authorities. Protocols should be revised on a regular basis to consider the incorporation of new cost-effective technologies.

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Crown‐rump length audit plots with the use of operator‐specific PAPP‐A and β‐hCG median MoM

Abstract: In sonologists with more than 100 NT measurements, operator-specific PAPP-A and β-hCG median MoM plots are able to identify deviations potentially related to a systematic CRL bias. Systematic underestimation above 2 mm was observed in 1/5 of them. © 2016 John Wiley & Sons, Ltd.

Cited by 5 publications

References 24 publications

Crown–rump length measurement error: impact on assessment of growth

Crown–rump length measurement error: impact on assessment of growth

Pre-Twin Screen - A Multi-Disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies

Prenatal screening and diagnosis of genetic abnormalities: SEGO, SEQC^ML, AEDP consensus recommendations

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Crown‐rump length audit plots with the use of operator‐specific PAPP‐A and β‐hCG median MoM

Abstract: In sonologists with more than 100 NT measurements, operator-specific PAPP-A and β-hCG median MoM plots are able to identify deviations potentially related to a systematic CRL bias. Systematic underestimation above 2 mm was observed in 1/5 of them. © 2016 John Wiley & Sons, Ltd.

Cited by 5 publications

References 24 publications

Crown–rump length measurement error: impact on assessment of growth

Crown–rump length measurement error: impact on assessment of growth

Pre-Twin Screen - A Multi-Disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies

Prenatal screening and diagnosis of genetic abnormalities: SEGO, SEQCML, AEDP consensus recommendations

Contact Info

Product

Resources

About

Prenatal screening and diagnosis of genetic abnormalities: SEGO, SEQC^ML, AEDP consensus recommendations