2022
DOI: 10.1096/fasebj.2022.36.s1.r5154
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CRY‐BAR: A versatile light‐gated tool for the remodeling of membrane architectures

Abstract: BAR (Bin, Amphiphysin and Rvs) protein domains are responsible for the generation of membrane curvature and represent a critical mechanical component of cellular function. Thus, BAR domains have great potential as components of membrane‐remodeling tools for cell biologists. In this work, we describe the design and implementation of a versatile light‐gated I‐BAR domain containing tool (‘CRY‐BAR’) with applications in the remodeling of membrane architectures and the control of cellular dynamics. By taking advant… Show more

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