Crystal structure of a C-type lysozyme from Litopenaeus vanamei exhibiting a high binding constant to its chitotriose inhibitor

Vargas-Requena, Claudia; Rodrı́guez-Romero, Adela; García-Ramírez, Benjamin; Sotelo‐Mundo, Rogerio R.; Hernández-Santoyo, Alejandra

doi:10.1016/j.fsi.2020.03.010

Cited by 4 publications

(2 citation statements)

References 32 publications

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“…Previous studies have shown that the Imd pathway transcription factor relish plays a central role in regulating the immune response (Li & Xiang, 2013a, 2013bZuo et al, 2016); C-type lectin is regarded as a potential molecule involved in the immune recognition and phagocytosis of crustaceans through opsonisation (Liu et al, 2007); proPO-b plays important role in the antibacterial response of crustaceans (Ai et al, 2008;Fagutao et al, 2009); antiviral protein, C-LSZ and cytoplasmic MnSOD are immune effector proteins with antibacterial and antiviral activities (Vargas-Requena et al, 2020;Lin et al, 2010;Liang et al, 2017;. In this study, after silencing the…”

Section: Role Of Mjchi4 In the Regulation Of Immune Effectors And Tra...mentioning

confidence: 79%

“…Previous studies have shown that the Imd pathway transcription factor relish plays a central role in regulating the immune response (Li & Xiang, 2013a, 2013b; Zuo et al, 2016); C‐type lectin is regarded as a potential molecule involved in the immune recognition and phagocytosis of crustaceans through opsonisation (Liu et al, 2007); proPO‐b plays important role in the antibacterial response of crustaceans (Ai et al, 2008; Fagutao et al, 2009); antiviral protein, C‐LSZ and cytoplasmic MnSOD are immune effector proteins with antibacterial and antiviral activities (Vargas‐Requena et al, 2020; Lin et al, 2010; Liang et al, 2017; Li, Li, et al, 2015). In this study, after silencing the MjChi4 gene through RNA interference in vivo, the expression of chitinase (MjChi1, MjChi2, and MjChi3), antiviral protein, C‐type lectin, C‐LSZ and proPO‐b genes decreased significantly; by contrast, the expression of cytosolic MnSOD and the transcription factor relish was upregulated in MjChi4 gene‐silenced shrimp.…”

Section: Discussionmentioning

confidence: 99%

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Characterization and functional analysis of MjChi4 from the kuruma shrimp Marsupenaeus japonicus under the environmental stresses low pH and high ammonia

Liang

et al. 2021

Aquaculture Research

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Members of the multi-gene family chitinase (Chi) occur in a broad range of organisms (Huang et al., 2009;Li, 2013). To date, hundreds of crustacean chitinase genes have been identified. The crustacean chitinase genes were first isolated and characterized in Marsupenaeus japonicus (Watanabe & Kono, 1997;Watanabe, Kono, Aida, & Nagasawa, 1996, 1998, and more chitinase genes were subsequently cloned in various crustacean species. Five chitinase genes have been identified in Eriocheir sinensis ; four chitinases (EcChi1-EcChi4) have been identified in Exopalaemon carinicauda (Wang et al., 2015); seven kinds of chitinase cDNA have

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Section: Role Of Mjchi4 In the Regulation Of Immune Effectors And Tra...mentioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Characterization and functional analysis of MjChi4 from the kuruma shrimp Marsupenaeus japonicus under the environmental stresses low pH and high ammonia

Liang

et al. 2021

Aquaculture Research

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Molecular characterization and expression analysis of the chicken-type and goose-type lysozymes from totoaba (Totoaba macdonaldi)

Moreno-Córdova

Islas-Osuna

Contreras-Vergara

et al. 2020

Developmental & Comparative Immunology

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The expanding repertoire of immune‐related molecules with antimicrobial activity in penaeid shrimps: a review

Aweya

Zheng

et al. 2021

Reviews in Aquaculture

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Shrimps live in a complex aquatic ecosystem with numerous other biotic and abiotic factors, especially pathogenic microorganisms, which require the adaptation of prudent protective and survival strategies. As invertebrates, shrimps reply on humoral and cellular innate immune response mechanisms for protection against pathogens. One integral part of the humoral innate immune defence mechanism involves many biomolecules that are constitutively expressed or induced by pathogens. Shrimps, therefore, produce various biomolecules and secondary metabolites for physiological and pathophysiological purposes, most of which also act as effector molecules in immune-related functions. A growing number of molecules have been identified as essential constituents of the immune arsenal of biomolecules in penaeid shrimps. This review provides a synthesis of important information on penaeid shrimp-encoded immune-related molecules with antimicrobial activities, their molecular regulation and importance in shrimp innate immune response. Research gaps would be identified and proposed research themes emphasized for future studies.

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Crystal structure of a C-type lysozyme from Litopenaeus vanamei exhibiting a high binding constant to its chitotriose inhibitor

Cited by 4 publications

References 32 publications

Characterization and functional analysis of MjChi4 from the kuruma shrimp Marsupenaeus japonicus under the environmental stresses low pH and high ammonia

Characterization and functional analysis of MjChi4 from the kuruma shrimp Marsupenaeus japonicus under the environmental stresses low pH and high ammonia

Molecular characterization and expression analysis of the chicken-type and goose-type lysozymes from totoaba (Totoaba macdonaldi)

The expanding repertoire of immune‐related molecules with antimicrobial activity in penaeid shrimps: a review

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