Crystal structures of two chiral piperidine derivatives: 1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-4-one and 8-[(1S)-1-phenylethyl]-1,4-dioxa-8-azaspiro[4.5]decane-7-thione

Abstract

The conformation of the piperidine ring is modified by the hybridization state of the C atom in the α-position to the piperidinic N atom.