Crystal structures of two substituted thiazolidine derivatives

Abstract

In both compounds, namely 2′-ferrocenyl-6′-methyl-6a’-nitro-6′,6a’,6b’,7′,9′,11a’-hexa­hydro-2H-spiro­[ace­naphthyl­ene-1,11′-chromeno[3′,4′:3,4]pyrrolo­[1,2-c]thia­zol]-2-one, (I), and 6′-(4-meth­oxy­phen­yl)-6a’-nitro-6′,6a’,6b’,7′,9′,11a’-hexa­hydro-2H-spiro­[ace­naphthyl­ene-1,11′-chromeno[3′,4′:3,4]pyrrolo­[1,2-c]thia­zol]-2-one, (II), an intra­molecular C—H⋯O hydrogen bond forms an S(7) ring motif. In (I), mol­ecules are linked via two different C—H⋯O hydrogen bonds, forming chains along [001] and [100]. In (II), they are linked through C—H⋯O hydrogen bonds, forming dimers with an (10) ring motif while C—H⋯π inter­actions link the mol­ecules in a head-to-tail fashion, forming chains along the a-axis direction.

Advances in the Synthesis of Benzo‐Fused Spiro Nitrogen Heterocycles: New Approaches and Modification of Old Strategies

“…The synthesis and study of the properties of new spiro‐fused carbo and heterocyclic compounds are one of the priority areas of investigations in organic chemistry, the results of which are of both theoretical interest and practical importance for a large number of researchers. These studies have been presented to the chemical community in original articles, [1–26] in thematic reviews, [27–35] as well as in review articles on the synthesis of some other heterocycles where spiro analogs are mentioned in one way or another [36,37] . The topic of spiro‐fused heterocycles is quite wide and therefore often touched upon when studying the chemistry of natural compounds, [38,39] in review articles [40] on the use of individual organic compounds in the synthesis of alkaloids, [41] in the enantioselective synthesis of hetero and carbocycles [42] or their macrocyclic analogs [43,44] …”