Crystallization kinetics of PGBG4: A sequential poly(ester amide) derived from glycine, 1,4‐butanediol, and adipic acid

Abstract

Isothermal crystallization kinetics of a new sequential poly(ester amide) derived from glycine, 1,4‐butanediol, and adipic acid was investigated with differential scanning calorimetry and optical microscopy. The Avrami analysis was performed to obtain the kinetic parameters of primary and secondary crystallization. The experimental data indicate a heterogeneous nucleation with spherical growth geometry for the primary crystallization, whereas a linear growth within formed spherulites is characteristic of the last crystallization stages. The Lauritzen–Hoffman analysis was also undertaken to determine the different crystallization regimes, having estimated the corresponding nucleation constants. Temperature dependence of the normalized crystallization‐rate constants was tested with different theoretical equations. These allow an estimation of a temperature close to 90 °C for the maximum crystallization rate. © 2003 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 41: 903–912, 2003

Synthesis and Characterization of a New Degradable Poly(ester amide) Derived from 6-Amino-1-hexanol and Glutaric Acid

“…Spherulites could be obtained when samples crystallize from the melt state, in agreement with the mean value of 2.3 for the Avrami exponent. A negative birefingence is observed, as usual for polyesters and also for different poly(ester amides). , Numerous nuclei appear and spherulites quickly develop, reaching a small diameter (Figure a) that makes difficult an accurate analysis of the crystal growth. Solution-grown spherulites are also negative but can reach a larger diameter if the solvent evaporation is slow (Figure b).…”

Concept and Synthesis of Poly(ester amide)s with One Isolated, Two or Three Consecutive Amide Bonds Randomly Distributed Along the Polyester Backbone

“…The incorporation of amino acids makes the polymer biocompatible. Preformed monomers can be synthesized by condensing amino acids such as alanine or glycine with diols to form diester-diamine salts which are then reacted with dicarboxylic acids or their dichlorides to form alternating PEAs [41,43,47,48,[51][52][53][54][55][61][62][63]. α,ω-Amino-alcohols-based alternating PEAs can also be obtained by condensing dicarboxylic acids with linear aliphatic amino alcohols with varying numbers of methylene groups [41,64].…”