CT enterography-based radiomics combined with body composition to predict infliximab treatment failure in Crohn’s disease

Song, Fulong; Ma, Mengtian; Zeng, Shumin; Shao, Fang; Huang, Weiyan; Feng, Zhichao; Rong, Pengfei

doi:10.1007/s11547-023-01748-w

Cited by 4 publications

(1 citation statement)

References 45 publications

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“…This is critical not only by a medico-legal point of view, but also by a "human" point of view, because, like Coppola et al [81] stressed, we must not superintend the meaning of the irreplaceable doctor-patient bond. Connecting doctors and patients directly will always be an important phase of healthcare services that artificial intelligence can never replace [2,20,68,[102][103][104][105][106][107][108][109].…”

Section: Discussionmentioning

confidence: 99%

An Informative Review of Radiomics Studies on Cancer Imaging: The Main Findings, Challenges and Limitations of the Methodologies

Fusco,

Granata,

Simonetti

et al. 2024

Current Oncology

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The aim of this informative review was to investigate the application of radiomics in cancer imaging and to summarize the results of recent studies to support oncological imaging with particular attention to breast cancer, rectal cancer and primitive and secondary liver cancer. This review also aims to provide the main findings, challenges and limitations of the current methodologies. Clinical studies published in the last four years (2019–2022) were included in this review. Among the 19 studies analyzed, none assessed the differences between scanners and vendor-dependent characteristics, collected images of individuals at additional points in time, performed calibration statistics, represented a prospective study performed and registered in a study database, conducted a cost-effectiveness analysis, reported on the cost-effectiveness of the clinical application, or performed multivariable analysis with also non-radiomics features. Seven studies reached a high radiomic quality score (RQS), and seventeen earned additional points by using validation steps considering two datasets from two distinct institutes and open science and data domains (radiomics features calculated on a set of representative ROIs are open source). The potential of radiomics is increasingly establishing itself, even if there are still several aspects to be evaluated before the passage of radiomics into routine clinical practice. There are several challenges, including the need for standardization across all stages of the workflow and the potential for cross-site validation using real-world heterogeneous datasets. Moreover, multiple centers and prospective radiomics studies with more samples that add inter-scanner differences and vendor-dependent characteristics will be needed in the future, as well as the collecting of images of individuals at additional time points, the reporting of calibration statistics and the performing of prospective studies registered in a study database.

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