CT findings of glutaraldehyde colitis: A report of two cases

Zissin, Rivka; Gayer, Gabriela; Maor-Kendler, Yaakov

doi:10.1016/s0009-9260(99)91073-5

Cited by 14 publications

(8 citation statements)

References 6 publications

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“…The child finally recovered without sequelae. It was reported that colitis was induced by retention of 2% GA disinfectant in endoscope channels 23,24) . The acute toxicity of GA has been investigated in many studies with various animal species 2,[25][26][27] .…”

Section: Acute Toxicitymentioning

confidence: 99%

Effects of Glutaraldehyde Exposure on Human Health

Takigawa

Endo

2006

Journal of Occupational Health

248

147

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Section: Acute Toxicitymentioning

confidence: 99%

Effects of Glutaraldehyde Exposure on Human Health

Takigawa

Endo

2006

Journal of Occupational Health

248

147

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“…[5][6][7][8][9][10][11][12] Additional studies have found an association between residual glutaraldehyde on endoscopes and colitis symptoms in patients without UC. [13][14][15][16][17][18][19][20][21][22][23] However, no trials have directly assessed the impact of colonoscopy on UC symptoms. Anecdotally, we have noted an increase in symptoms in UC patients after colonoscopy.…”

mentioning

confidence: 99%

Does colonoscopy cause increased ulcerative colitis symptoms?

Menees

Higgins

Korsnes

et al. 2007

Inflammatory Bowel Diseases

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“…Reports of human exposure to GA and QACs are limited to a few individual cases [3][4][5] and there are no reports of acute ingestion. The lack of reports is likely due to its lack of common use in domestic or agricultural settings.…”

Section: Discussionmentioning

confidence: 99%

Laryngeal edema and metabolic acidosis after Omnicide® ingestion

Perera¹,

Kularathne²,

Gawarammana³

2008

Clinical Toxicology

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Introduction. Glutaraldehyde and quaternary ammonium compounds are widely used as disinfectants and sterilizing agents. Glutaraldehyde is irritating to the eyes and upper respiratory tract, and has been associated with occupational asthma. Acute oral ingestion of a concentrated solution has not been previously reported in humans. Case Report. A 19-year-old woman presented after deliberate ingestion of a biocide containing glutaraldehyde and a quaternary ammonium compound. She developed respiratory distress and severe metabolic acidosis 10 hours after admission. Marked laryngeal edema was noted when she was being intubated. She eventually improved following supportive care and was discharged alive after 9 hospital days. Discussion. There are no reports of acute ingestions of both glutaraldehyde and quaternary ammonium compounds. As both these substances are known to cause metabolic acidosis, localized edema, erosion and sensitization of both the respiratory and alimentary tract. The clinical effect may be additive or synergistic. Conclusions. Omnicide ingestion should be closely monitored for metabolic acidosis and laryngeal edema which may progress to upper airway obstruction requiring urgent airway stabilization.

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CT findings of glutaraldehyde colitis: A report of two cases

Cited by 14 publications

References 6 publications

Effects of Glutaraldehyde Exposure on Human Health

Effects of Glutaraldehyde Exposure on Human Health

Does colonoscopy cause increased ulcerative colitis symptoms?

Laryngeal edema and metabolic acidosis after Omnicide® ingestion

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